1489 lines
No EOL
93 KiB
XML
1489 lines
No EOL
93 KiB
XML
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<comp:externalModelDefinition comp:id="AraCsensor_module" comp:md5="aea8373d33ed14e7c0d1ad9301f057c6" comp:source="AraCsensor_module.xml"/>
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<comp:externalModelDefinition comp:id="LacIsensor_module" comp:md5="d93c75be779f6d6d012d54aa4ed92fa2" comp:source="LacIsensor_module.xml"/>
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<comp:externalModelDefinition comp:id="PhlFpart_module" comp:md5="2ff643eee1924804a82932e7426dce25" comp:source="PhlFpart_module.xml"/>
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<comp:externalModelDefinition comp:id="HlyIIRpart_module" comp:md5="ed81d2f77d29e03f03e172aded9b2780" comp:source="HlyIIRpart_module.xml"/>
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<comp:submodel comp:id="topModel_PhlFpart_module_sub" comp:modelRef="PhlFpart_module" metaid="iBioSim61">
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<annotation>
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<annotation>
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</annotation>
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<rdf:li rdf:resource="http://www.async.utah.edu/topModel/topModel_YFPpart_module_sub/topModel_YFPpart_module_sub_PhlF_protein_PhlF_protein"/></rdf:Bag></mts:MapsTos></rdf:Description></rdf:RDF></ModelToSBOL>
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</annotation>
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<comp:replacedElement comp:portRef="output__PhlF_protein" comp:submodelRef="topModel_PhlFpart_module_sub" metaid="iBioSim58">
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<rdf:li rdf:resource="http://www.async.utah.edu/topModel/topModel_PhlFpart_module_sub/topModel_PhlFpart_module_sub_PhlF_protein_PhlF_protein"/></rdf:Bag></mts:MapsTos></rdf:Description></rdf:RDF></ModelToSBOL>
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</annotation>
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<species boundaryCondition="false" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="YFP_protein" initialAmount="0" metaid="iBioSim14" sboTerm="SBO:0000252">
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<annotation>
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<rdf:Bag>
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<rdf:li rdf:resource="https://synbiohub.programmingbiology.org/public/Eco1C1G1T1/YFP_protein/1"/></rdf:Bag></mts:FunctionalComponents></rdf:Description></rdf:RDF></ModelToSBOL>
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<comp:replacedElement comp:portRef="output__YFP_protein" comp:submodelRef="topModel_YFPpart_module_sub" metaid="iBioSim46">
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<rdf:Description rdf:about="#iBioSim46">
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<rdf:li rdf:resource="http://www.async.utah.edu/topModel/topModel_YFPpart_module_sub/topModel_YFPpart_module_sub_YFP_protein_YFP_protein"/></rdf:Bag></mts:MapsTos></rdf:Description></rdf:RDF></ModelToSBOL>
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</annotation>
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<species boundaryCondition="true" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="Ara" initialAmount="60" metaid="iBioSim15" sboTerm="SBO:0000247">
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<annotation>
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<rdf:Description rdf:about="#iBioSim15">
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<rdf:Bag>
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|
|
<rdf:Seq>
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<rdf:li rdf:resource="https://synbiohub.programmingbiology.org/public/Eco1C1G1T1/Ara/1"/></rdf:Seq></mts:DNAComponents><mts:Strand>+</mts:Strand></rdf:Description></rdf:RDF></ModelToSBOL>
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</annotation>
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<listOfParameters>
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<parameter constant="true" id="kd" metaid="iBioSim1" name="Degradation rate" value="0.0075"/>
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<parameter constant="true" id="kc_f" metaid="iBioSim66" name="Forward complex formation rate" value="0.05"/>
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<parameter constant="true" id="kc_r" metaid="iBioSim67" name="Reverse complex formation rate" value="1"/>
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<parameter constant="true" id="nc" metaid="iBioSim68" name="Stoichiometry of binding" value="2"/>
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</listOfParameters>
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<listOfInitialAssignments/>
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<listOfConstraints>
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<constraint metaid="c0">
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<math xmlns="http://www.w3.org/1998/Math/MathML">
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<apply>
|
|
<lt/>
|
|
<ci> YFP_protein </ci>
|
|
<cn type="integer"> 30 </cn>
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</apply>
|
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</math>
|
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</constraint>
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|
</listOfConstraints>
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<reaction compartment="Cell" id="AraC_degradation_interaction" metaid="iBioSim69" reversible="false" sboTerm="SBO:0000179">
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<annotation>
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|
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</annotation>
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<listOfReactants>
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<speciesReference constant="true" metaid="iBioSim16" species="AraC_protein" stoichiometry="1">
|
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<annotation>
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<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
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<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
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<rdf:Description rdf:about="#iBioSim16">
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</annotation>
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<kineticLaw>
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<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<times/>
|
|
<ci> kd </ci>
|
|
<ci> AraC_protein </ci>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Complex_aTc_TetR_protein" metaid="iBioSim17" reversible="true" sboTerm="SBO:0000177">
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<annotation>
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<rdf:Description rdf:about="#iBioSim17">
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|
|
</annotation>
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|
<listOfReactants>
|
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<speciesReference constant="true" metaid="iBioSim19" species="TetR_protein" stoichiometry="2">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
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<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
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|
<rdf:Description rdf:about="#iBioSim19">
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|
<rdf:Bag>
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</annotation>
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</speciesReference>
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|
<speciesReference constant="true" metaid="iBioSim20" species="aTc" stoichiometry="2">
|
|
<annotation>
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|
<rdf:Description rdf:about="#iBioSim20">
|
|
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|
|
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|
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|
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</annotation>
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|
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|
|
<listOfProducts>
|
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|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
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|
|
<rdf:Description rdf:about="#iBioSim18">
|
|
<mts:Participations>
|
|
<rdf:Bag>
|
|
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|
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</annotation>
|
|
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|
|
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|
|
<kineticLaw>
|
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<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<minus/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<ci> kc_f </ci>
|
|
<apply>
|
|
<power/>
|
|
<ci> TetR_protein </ci>
|
|
<ci> nc </ci>
|
|
</apply>
|
|
</apply>
|
|
<apply>
|
|
<power/>
|
|
<ci> aTc </ci>
|
|
<ci> nc </ci>
|
|
</apply>
|
|
</apply>
|
|
<apply>
|
|
<times/>
|
|
<ci> kc_r </ci>
|
|
<ci> aTc_TetR_protein </ci>
|
|
</apply>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
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|
|
<reaction compartment="Cell" id="TetR_degradation_interaction" metaid="iBioSim70" reversible="false" sboTerm="SBO:0000179">
|
|
<annotation>
|
|
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|
|
<rdf:Description rdf:about="#">
|
|
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|
|
<rdf:Bag>
|
|
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|
|
</annotation>
|
|
<listOfReactants>
|
|
<speciesReference constant="true" metaid="iBioSim21" species="TetR_protein" stoichiometry="1">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#iBioSim21">
|
|
<mts:Participations>
|
|
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|
|
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|
|
</annotation>
|
|
</speciesReference>
|
|
</listOfReactants>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<times/>
|
|
<ci> kd </ci>
|
|
<ci> TetR_protein </ci>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Ara_AraC_protein_degradation_interaction" metaid="iBioSim71" reversible="false" sboTerm="SBO:0000179">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
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|
|
<rdf:Description rdf:about="#">
|
|
<mts:Interactions>
|
|
<rdf:Bag>
|
|
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|
|
</annotation>
|
|
<listOfReactants>
|
|
<speciesReference constant="true" metaid="iBioSim22" species="Ara_AraC_protein" stoichiometry="1">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#iBioSim22">
|
|
<mts:Participations>
|
|
<rdf:Bag>
|
|
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|
|
</annotation>
|
|
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|
|
</listOfReactants>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<times/>
|
|
<ci> kd </ci>
|
|
<ci> Ara_AraC_protein </ci>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="IPTG_LacI_protein_degradation_interaction" metaid="iBioSim72" reversible="false" sboTerm="SBO:0000179">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#">
|
|
<mts:Interactions>
|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/IPTG_LacI_protein_degradation_interaction"/></rdf:Bag></mts:Interactions></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
|
|
<listOfReactants>
|
|
<speciesReference constant="true" metaid="iBioSim23" species="IPTG_LacI_protein" stoichiometry="1">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#iBioSim23">
|
|
<mts:Participations>
|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/IPTG_LacI_protein"/></rdf:Bag></mts:Participations></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
|
|
</speciesReference>
|
|
</listOfReactants>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<times/>
|
|
<ci> kd </ci>
|
|
<ci> IPTG_LacI_protein </ci>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="PhlF_degradation_interaction" metaid="iBioSim73" reversible="false" sboTerm="SBO:0000179">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#">
|
|
<mts:Interactions>
|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/PhlF_degradation_interaction"/></rdf:Bag></mts:Interactions></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
|
|
<listOfReactants>
|
|
<speciesReference constant="true" metaid="iBioSim24" species="PhlF_protein" stoichiometry="1">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#iBioSim24">
|
|
<mts:Participations>
|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/PhlF_protein"/></rdf:Bag></mts:Participations></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
|
|
</speciesReference>
|
|
</listOfReactants>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<times/>
|
|
<ci> kd </ci>
|
|
<ci> PhlF_protein </ci>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="aTc_TetR_protein_degradation_interaction" metaid="iBioSim74" reversible="false" sboTerm="SBO:0000179">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
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|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#">
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|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/aTc_TetR_protein_degradation_interaction"/></rdf:Bag></mts:Interactions></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
|
|
<listOfReactants>
|
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<speciesReference constant="true" metaid="iBioSim25" species="aTc_TetR_protein" stoichiometry="1">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
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<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
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<rdf:Description rdf:about="#iBioSim25">
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<mts:Participations>
|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/aTc_TetR_protein"/></rdf:Bag></mts:Participations></rdf:Description></rdf:RDF></ModelToSBOL>
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</annotation>
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</speciesReference>
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</listOfReactants>
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<kineticLaw>
|
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<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<times/>
|
|
<ci> kd </ci>
|
|
<ci> aTc_TetR_protein </ci>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Complex_IPTG_LacI_protein" metaid="iBioSim26" reversible="true" sboTerm="SBO:0000177">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
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<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
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|
<rdf:Description rdf:about="#iBioSim26">
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<mts:Interactions>
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|
<rdf:Bag>
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|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/IPTG_LacI_protein_complex_formation"/></rdf:Bag></mts:Interactions></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
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<listOfReactants>
|
|
<speciesReference constant="true" metaid="iBioSim28" species="IPTG" stoichiometry="2">
|
|
<annotation>
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|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
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<rdf:Description rdf:about="#iBioSim28">
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<mts:Participations>
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<rdf:Bag>
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<rdf:li rdf:resource="http://www.async.utah.edu/topModel/IPTG"/></rdf:Bag></mts:Participations></rdf:Description></rdf:RDF></ModelToSBOL>
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|
</annotation>
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|
</speciesReference>
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|
<speciesReference constant="true" metaid="iBioSim29" species="LacI_protein" stoichiometry="2">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
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<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
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<rdf:Description rdf:about="#iBioSim29">
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<mts:Participations>
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|
<rdf:Bag>
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|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/LacI_protein"/></rdf:Bag></mts:Participations></rdf:Description></rdf:RDF></ModelToSBOL>
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</annotation>
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</speciesReference>
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|
</listOfReactants>
|
|
<listOfProducts>
|
|
<speciesReference constant="true" metaid="iBioSim27" species="IPTG_LacI_protein" stoichiometry="1">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#iBioSim27">
|
|
<mts:Participations>
|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/IPTG_LacI_protein"/></rdf:Bag></mts:Participations></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
|
|
</speciesReference>
|
|
</listOfProducts>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<minus/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<ci> kc_f </ci>
|
|
<apply>
|
|
<power/>
|
|
<ci> IPTG </ci>
|
|
<ci> nc </ci>
|
|
</apply>
|
|
</apply>
|
|
<apply>
|
|
<power/>
|
|
<ci> LacI_protein </ci>
|
|
<ci> nc </ci>
|
|
</apply>
|
|
</apply>
|
|
<apply>
|
|
<times/>
|
|
<ci> kc_r </ci>
|
|
<ci> IPTG_LacI_protein </ci>
|
|
</apply>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="YFP_degradation_interaction" metaid="iBioSim75" reversible="false" sboTerm="SBO:0000179">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#">
|
|
<mts:Interactions>
|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/YFP_degradation_interaction"/></rdf:Bag></mts:Interactions></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
|
|
<listOfReactants>
|
|
<speciesReference constant="true" metaid="iBioSim30" species="YFP_protein" stoichiometry="1">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#iBioSim30">
|
|
<mts:Participations>
|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/YFP_protein"/></rdf:Bag></mts:Participations></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
|
|
</speciesReference>
|
|
</listOfReactants>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<times/>
|
|
<ci> kd </ci>
|
|
<ci> YFP_protein </ci>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="LacI_degradation_interaction" metaid="iBioSim76" reversible="false" sboTerm="SBO:0000179">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#">
|
|
<mts:Interactions>
|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/LacI_degradation_interaction"/></rdf:Bag></mts:Interactions></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
|
|
<listOfReactants>
|
|
<speciesReference constant="true" metaid="iBioSim31" species="LacI_protein" stoichiometry="1">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#iBioSim31">
|
|
<mts:Participations>
|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/LacI_protein"/></rdf:Bag></mts:Participations></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
|
|
</speciesReference>
|
|
</listOfReactants>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<times/>
|
|
<ci> kd </ci>
|
|
<ci> LacI_protein </ci>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Complex_Ara_AraC_protein" metaid="iBioSim32" reversible="true" sboTerm="SBO:0000177">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#iBioSim32">
|
|
<mts:Interactions>
|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/Ara_AraC_protein_complex_formation"/></rdf:Bag></mts:Interactions></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
|
|
<listOfReactants>
|
|
<speciesReference constant="true" metaid="iBioSim34" species="AraC_protein" stoichiometry="2">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#iBioSim34">
|
|
<mts:Participations>
|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/AraC_protein"/></rdf:Bag></mts:Participations></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
|
|
</speciesReference>
|
|
<speciesReference constant="true" metaid="iBioSim35" species="Ara" stoichiometry="2">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#iBioSim35">
|
|
<mts:Participations>
|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/Ara"/></rdf:Bag></mts:Participations></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
|
|
</speciesReference>
|
|
</listOfReactants>
|
|
<listOfProducts>
|
|
<speciesReference constant="true" metaid="iBioSim33" species="Ara_AraC_protein" stoichiometry="1">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#iBioSim33">
|
|
<mts:Participations>
|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/Ara_AraC_protein"/></rdf:Bag></mts:Participations></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
|
|
</speciesReference>
|
|
</listOfProducts>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<minus/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<ci> kc_f </ci>
|
|
<apply>
|
|
<power/>
|
|
<ci> AraC_protein </ci>
|
|
<ci> nc </ci>
|
|
</apply>
|
|
</apply>
|
|
<apply>
|
|
<power/>
|
|
<ci> Ara </ci>
|
|
<ci> nc </ci>
|
|
</apply>
|
|
</apply>
|
|
<apply>
|
|
<times/>
|
|
<ci> kc_r </ci>
|
|
<ci> Ara_AraC_protein </ci>
|
|
</apply>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="HlyIIR_degradation_interaction" metaid="iBioSim77" reversible="false" sboTerm="SBO:0000179">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#">
|
|
<mts:Interactions>
|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/HlyIIR_degradation_interaction"/></rdf:Bag></mts:Interactions></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
|
|
<listOfReactants>
|
|
<speciesReference constant="true" metaid="iBioSim36" species="HlyIIR_protein" stoichiometry="1">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#iBioSim36">
|
|
<mts:Participations>
|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/HlyIIR_protein"/></rdf:Bag></mts:Participations></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
|
|
</speciesReference>
|
|
</listOfReactants>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<times/>
|
|
<ci> kd </ci>
|
|
<ci> HlyIIR_protein </ci>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="BetI_degradation_interaction" metaid="iBioSim78" reversible="false" sboTerm="SBO:0000179">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#">
|
|
<mts:Interactions>
|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/BetI_degradation_interaction"/></rdf:Bag></mts:Interactions></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
|
|
<listOfReactants>
|
|
<speciesReference constant="true" metaid="iBioSim37" species="BetI_protein" stoichiometry="1">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#iBioSim37">
|
|
<mts:Participations>
|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/BetI_protein"/></rdf:Bag></mts:Participations></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
|
|
</speciesReference>
|
|
</listOfReactants>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<times/>
|
|
<ci> kd </ci>
|
|
<ci> BetI_protein </ci>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="AmtR_degradation_interaction" metaid="iBioSim79" reversible="false" sboTerm="SBO:0000179">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#">
|
|
<mts:Interactions>
|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/AmtR_degradation_interaction"/></rdf:Bag></mts:Interactions></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
|
|
<listOfReactants>
|
|
<speciesReference constant="true" metaid="iBioSim38" species="AmtR_protein" stoichiometry="1">
|
|
<annotation>
|
|
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#">
|
|
<rdf:Description rdf:about="#iBioSim38">
|
|
<mts:Participations>
|
|
<rdf:Bag>
|
|
<rdf:li rdf:resource="http://www.async.utah.edu/topModel/AmtR_protein"/></rdf:Bag></mts:Participations></rdf:Description></rdf:RDF></ModelToSBOL>
|
|
</annotation>
|
|
</speciesReference>
|
|
</listOfReactants>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<times/>
|
|
<ci> kd </ci>
|
|
<ci> AmtR_protein </ci>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
</listOfReactions>
|
|
<listOfEvents/>
|
|
</model>
|
|
</sbml> |