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iBioSim Learn
The learn project includes parameter estimation and a regulatory network learning method from time-series data based on the GeneNet procedure.
How to use it:
After building the executable jar, you need to invoke the following command:
java -jar target/iBioSim-learn-3.0.0-SNAPSHOT-jar-with-dependencies.jar [-e] [-l ...] input directory
where
inputis an arbitrary SBML filedirectoryis the location of the time-series data-eis a flag to perform parameter estimation. Default is GeneNet.-l ...is a flag to specify which parameters need to be estimated, where the value is a comma separated list of parameter ids (e.g., "p1,p2,p3").