1770 lines
81 KiB
XML
1770 lines
81 KiB
XML
<?xml version='1.0' encoding='UTF-8' standalone='no'?>
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<sbml xmlns="http://www.sbml.org/sbml/level3/version2/core" comp:required="true" fbc:required="false" layout:required="false" level="2" version="2" xmlns:comp="http://www.sbml.org/sbml/level3/version1/comp/version1" xmlns:fbc="http://www.sbml.org/sbml/level3/version1/fbc/version2" xmlns:layout="http://www.sbml.org/sbml/level3/version1/layout/version1">
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<model id="Speed_Independent" metaid="iBioSim11">
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<comp:listOfPorts xmlns:comp="http://www.sbml.org/sbml/level3/version1/comp/version1">
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<comp:port comp:id="compartment__Cell" comp:idRef="Cell" sboTerm="SBO:0000601"/>
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<comp:port comp:id="input__B" comp:idRef="B" sboTerm="SBO:0000600"/>
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<comp:port comp:id="output__C" comp:idRef="C" sboTerm="SBO:0000601"/>
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<comp:port comp:id="reaction__Degradation_C" comp:idRef="Degradation_C" sboTerm="SBO:0000601"/>
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</comp:listOfPorts>
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<layout:listOfLayouts xmlns:layout="http://www.sbml.org/sbml/level3/version1/layout/version1" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
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<layout:layout layout:id="iBioSim">
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<layout:dimensions layout:depth="0" layout:height="425" layout:width="1070"/>
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<layout:listOfAdditionalGraphicalObjects>
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<layout:generalGlyph layout:id="Glyph__c0" layout:metaidRef="c0">
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<layout:listOfReferenceGlyphs>
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<layout:referenceGlyph layout:glyph="Glyph__S3" layout:id="Glyph__c0__substrate__S3" layout:role="substrate">
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<layout:dimensions layout:height="30" layout:width="100"/>
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<layout:dimensions layout:height="30" layout:width="100"/>
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</layout:speciesGlyph>
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<layout:speciesGlyph layout:id="Glyph__S3" layout:species="S3">
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<layout:boundingBox>
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<layout:dimensions layout:height="30" layout:width="100"/>
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<layout:speciesGlyph layout:id="Glyph__S4" layout:species="S4">
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<layout:boundingBox>
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<layout:position layout:x="300" layout:y="75"/>
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<layout:dimensions layout:height="30" layout:width="100"/>
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<layout:dimensions layout:height="30" layout:width="100"/>
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<layout:speciesGlyph layout:id="Glyph__Y" layout:species="Y">
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<layout:speciesGlyph layout:id="Glyph__Z" layout:species="Z">
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<layout:position layout:x="900" layout:y="15"/>
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<layout:dimensions layout:height="30" layout:width="100"/>
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<layout:speciesGlyph layout:id="Glyph__C" layout:species="C">
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<layout:boundingBox>
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<layout:position layout:x="880" layout:y="360"/>
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<layout:dimensions layout:height="30" layout:width="100"/>
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</layout:speciesGlyph>
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<layout:speciesGlyph layout:id="Glyph__P10" layout:species="P10">
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<layout:dimensions layout:height="30" layout:width="100"/>
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<layout:boundingBox>
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<layout:dimensions layout:height="30" layout:width="100"/>
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<layout:speciesGlyph layout:id="Glyph__P2" layout:species="P2">
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<layout:boundingBox>
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<layout:position layout:x="150" layout:y="105"/>
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<layout:dimensions layout:height="30" layout:width="100"/>
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</layout:boundingBox>
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</layout:speciesGlyph>
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<layout:speciesGlyph layout:id="Glyph__P3" layout:species="P3">
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<layout:dimensions layout:height="30" layout:width="100"/>
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</layout:speciesGlyph>
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<layout:speciesGlyph layout:id="Glyph__P4" layout:species="P4">
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<layout:boundingBox>
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<layout:position layout:x="450" layout:y="60"/>
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<layout:dimensions layout:height="30" layout:width="100"/>
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</layout:boundingBox>
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</layout:speciesGlyph>
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<layout:speciesGlyph layout:id="Glyph__P5" layout:species="P5">
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<layout:boundingBox>
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<layout:position layout:x="750" layout:y="120"/>
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<layout:dimensions layout:height="30" layout:width="100"/>
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</layout:boundingBox>
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</layout:speciesGlyph>
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<layout:speciesGlyph layout:id="Glyph__P6" layout:species="P6">
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<layout:boundingBox>
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<layout:position layout:x="940" layout:y="190"/>
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<layout:dimensions layout:height="30" layout:width="100"/>
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</layout:boundingBox>
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</layout:speciesGlyph>
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<layout:speciesGlyph layout:id="Glyph__P7" layout:species="P7">
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<layout:boundingBox>
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<layout:position layout:x="450" layout:y="150"/>
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<layout:dimensions layout:height="30" layout:width="100"/>
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</layout:boundingBox>
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</layout:speciesGlyph>
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<layout:speciesGlyph layout:id="Glyph__P8" layout:species="P8">
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<layout:boundingBox>
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<layout:position layout:x="750" layout:y="60"/>
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<layout:dimensions layout:height="30" layout:width="100"/>
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</layout:boundingBox>
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</layout:speciesGlyph>
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<layout:speciesGlyph layout:id="Glyph__P9" layout:species="P9">
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<layout:boundingBox>
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<layout:position layout:x="900" layout:y="70"/>
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<layout:dimensions layout:height="30" layout:width="100"/>
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</layout:boundingBox>
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</layout:speciesGlyph>
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<layout:speciesGlyph layout:id="Glyph__X" layout:species="X">
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<layout:boundingBox>
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<layout:position layout:x="300" layout:y="15"/>
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<layout:dimensions layout:height="30" layout:width="100"/>
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</layout:listOfSpeciesGlyphs>
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<layout:listOfReactionGlyphs>
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<layout:reactionGlyph layout:id="Glyph__Degradation_S4" layout:reaction="Degradation_S4">
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<layout:boundingBox>
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<layout:position layout:x="20" layout:y="30"/>
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<layout:dimensions layout:height="20" layout:width="20"/>
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<layout:listOfSpeciesReferenceGlyphs>
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<layout:speciesReferenceGlyph layout:id="Glyph__Degradation_S4__substrate__S4" layout:role="substrate" layout:speciesGlyph="Glyph__S4">
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</layout:reactionGlyph>
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<layout:reactionGlyph layout:id="Glyph__Degradation_S1" layout:reaction="Degradation_S1">
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<layout:boundingBox>
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<layout:position layout:x="40" layout:y="60"/>
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<layout:dimensions layout:height="20" layout:width="20"/>
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<layout:listOfSpeciesReferenceGlyphs>
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<layout:speciesReferenceGlyph layout:id="Glyph__Degradation_S1__substrate__S1" layout:role="substrate" layout:speciesGlyph="Glyph__S1">
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<layout:reactionGlyph layout:id="Glyph__Degradation_Z" layout:reaction="Degradation_Z">
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<layout:listOfSpeciesReferenceGlyphs>
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|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__S2" layout:id="TextGlyph__S2" layout:text="S2">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="900" layout:y="105"/>
|
|
<layout:dimensions layout:height="30" layout:width="100"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__S3" layout:id="TextGlyph__S3" layout:text="S3">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="600" layout:y="37"/>
|
|
<layout:dimensions layout:height="30" layout:width="100"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__S4" layout:id="TextGlyph__S4" layout:text="S4">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="300" layout:y="75"/>
|
|
<layout:dimensions layout:height="30" layout:width="100"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__B" layout:id="TextGlyph__B" layout:text="B">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="190" layout:y="260"/>
|
|
<layout:dimensions layout:height="30" layout:width="100"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__Y" layout:id="TextGlyph__Y" layout:text="Y">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="300" layout:y="135"/>
|
|
<layout:dimensions layout:height="30" layout:width="100"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__Z" layout:id="TextGlyph__Z" layout:text="Z">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="900" layout:y="15"/>
|
|
<layout:dimensions layout:height="30" layout:width="100"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__C" layout:id="TextGlyph__C" layout:text="C">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="880" layout:y="360"/>
|
|
<layout:dimensions layout:height="30" layout:width="100"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__P10" layout:id="TextGlyph__P10" layout:text="P10">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="603" layout:y="62"/>
|
|
<layout:dimensions layout:height="30" layout:width="100"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__P1" layout:id="TextGlyph__P1" layout:text="P1">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="150" layout:y="45"/>
|
|
<layout:dimensions layout:height="30" layout:width="100"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__P2" layout:id="TextGlyph__P2" layout:text="P2">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="150" layout:y="105"/>
|
|
<layout:dimensions layout:height="30" layout:width="100"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__P3" layout:id="TextGlyph__P3" layout:text="P3">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="450" layout:y="0"/>
|
|
<layout:dimensions layout:height="30" layout:width="100"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__P4" layout:id="TextGlyph__P4" layout:text="P4">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="450" layout:y="60"/>
|
|
<layout:dimensions layout:height="30" layout:width="100"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__P5" layout:id="TextGlyph__P5" layout:text="P5">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="750" layout:y="120"/>
|
|
<layout:dimensions layout:height="30" layout:width="100"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__P6" layout:id="TextGlyph__P6" layout:text="P6">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="940" layout:y="190"/>
|
|
<layout:dimensions layout:height="30" layout:width="100"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__P7" layout:id="TextGlyph__P7" layout:text="P7">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="450" layout:y="150"/>
|
|
<layout:dimensions layout:height="30" layout:width="100"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__P8" layout:id="TextGlyph__P8" layout:text="P8">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="750" layout:y="60"/>
|
|
<layout:dimensions layout:height="30" layout:width="100"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__P9" layout:id="TextGlyph__P9" layout:text="P9">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="900" layout:y="70"/>
|
|
<layout:dimensions layout:height="30" layout:width="100"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__X" layout:id="TextGlyph__X" layout:text="X">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="300" layout:y="15"/>
|
|
<layout:dimensions layout:height="30" layout:width="100"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__c0" layout:id="TextGlyph__c0" layout:text="c0">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="527" layout:y="313"/>
|
|
<layout:dimensions layout:height="40" layout:width="50"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__Degradation_S4" layout:id="TextGlyph__Degradation_S4" layout:text="Degradation_S4">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="20" layout:y="30"/>
|
|
<layout:dimensions layout:height="20" layout:width="20"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__Degradation_S1" layout:id="TextGlyph__Degradation_S1" layout:text="Degradation_S1">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="40" layout:y="60"/>
|
|
<layout:dimensions layout:height="20" layout:width="20"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__Degradation_Z" layout:id="TextGlyph__Degradation_Z" layout:text="Degradation_Z">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="60" layout:y="90"/>
|
|
<layout:dimensions layout:height="20" layout:width="20"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__Degradation_C" layout:id="TextGlyph__Degradation_C" layout:text="Degradation_C">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="80" layout:y="120"/>
|
|
<layout:dimensions layout:height="20" layout:width="20"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__Degradation_X" layout:id="TextGlyph__Degradation_X" layout:text="Degradation_X">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="100" layout:y="150"/>
|
|
<layout:dimensions layout:height="20" layout:width="20"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__Degradation_S2" layout:id="TextGlyph__Degradation_S2" layout:text="Degradation_S2">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="120" layout:y="180"/>
|
|
<layout:dimensions layout:height="20" layout:width="20"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__Degradation_S3" layout:id="TextGlyph__Degradation_S3" layout:text="Degradation_S3">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="140" layout:y="210"/>
|
|
<layout:dimensions layout:height="20" layout:width="20"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
<layout:textGlyph layout:graphicalObject="Glyph__Degradation_Y" layout:id="TextGlyph__Degradation_Y" layout:text="Degradation_Y">
|
|
<layout:boundingBox>
|
|
<layout:position layout:x="160" layout:y="240"/>
|
|
<layout:dimensions layout:height="20" layout:width="20"/>
|
|
</layout:boundingBox>
|
|
</layout:textGlyph>
|
|
</layout:listOfTextGlyphs>
|
|
</layout:layout>
|
|
</layout:listOfLayouts>
|
|
<listOfFunctionDefinitions>
|
|
<functionDefinition id="F" name="Eventually Property">
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<lambda>
|
|
<bvar>
|
|
<ci> t </ci>
|
|
</bvar>
|
|
<bvar>
|
|
<ci> x </ci>
|
|
</bvar>
|
|
<apply>
|
|
<or/>
|
|
<apply>
|
|
<not/>
|
|
<ci> t </ci>
|
|
</apply>
|
|
<apply>
|
|
<not/>
|
|
<ci> x </ci>
|
|
</apply>
|
|
</apply>
|
|
</lambda>
|
|
</math>
|
|
</functionDefinition>
|
|
</listOfFunctionDefinitions>
|
|
<listOfCompartments>
|
|
<compartment constant="true" id="Cell" size="1" spatialDimensions="3"/>
|
|
</listOfCompartments>
|
|
<listOfSpecies>
|
|
<species boundaryCondition="true" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="A" initialAmount="0" metaid="iBioSim1"/>
|
|
<species boundaryCondition="false" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="S1" initialAmount="70" metaid="iBioSim3"/>
|
|
<species boundaryCondition="false" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="S2" initialAmount="0" metaid="iBioSim4"/>
|
|
<species boundaryCondition="false" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="S3" initialAmount="70" metaid="iBioSim5"/>
|
|
<species boundaryCondition="false" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="S4" initialAmount="130" metaid="iBioSim6"/>
|
|
<species boundaryCondition="true" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="B" initialAmount="120" metaid="iBioSim7"/>
|
|
<species boundaryCondition="false" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="Y" initialAmount="0" metaid="iBioSim8"/>
|
|
<species boundaryCondition="false" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="Z" initialAmount="0" metaid="iBioSim9"/>
|
|
<species boundaryCondition="false" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="C" initialAmount="70" metaid="iBioSim10"/>
|
|
<species boundaryCondition="false" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="P10" initialAmount="2" metaid="iBioSim12" sboTerm="SBO:0000590"/>
|
|
<species boundaryCondition="false" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="P1" initialAmount="2" metaid="iBioSim14" sboTerm="SBO:0000590"/>
|
|
<species boundaryCondition="false" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="P2" initialAmount="2" metaid="iBioSim16" sboTerm="SBO:0000590"/>
|
|
<species boundaryCondition="false" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="P3" initialAmount="2" metaid="iBioSim18" sboTerm="SBO:0000590"/>
|
|
<species boundaryCondition="false" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="P4" initialAmount="2" metaid="iBioSim20" sboTerm="SBO:0000590"/>
|
|
<species boundaryCondition="false" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="P5" initialAmount="2" metaid="iBioSim22" sboTerm="SBO:0000590"/>
|
|
<species boundaryCondition="false" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="P6" initialAmount="2" metaid="iBioSim24" sboTerm="SBO:0000590"/>
|
|
<species boundaryCondition="false" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="P7" initialAmount="2" metaid="iBioSim26" sboTerm="SBO:0000590"/>
|
|
<species boundaryCondition="false" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="P8" initialAmount="2" metaid="iBioSim28" sboTerm="SBO:0000590"/>
|
|
<species boundaryCondition="false" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="P9" initialAmount="2" metaid="iBioSim30" sboTerm="SBO:0000590"/>
|
|
<species boundaryCondition="false" compartment="Cell" constant="false" hasOnlySubstanceUnits="true" id="X" initialAmount="70" metaid="iBioSim33"/>
|
|
</listOfSpecies>
|
|
<listOfParameters>
|
|
<parameter constant="true" id="kd" metaid="iBioSim2" name="Degradation rate" value="0.00075"/>
|
|
<parameter constant="true" id="kr_f" metaid="iBioSim13" name="Forward repression binding rate" value="0.5"/>
|
|
<parameter constant="true" id="kr_r" metaid="iBioSim34" name="Reverse repression binding rate" value="1"/>
|
|
<parameter constant="true" id="ka_f" metaid="iBioSim35" name="Forward activation binding rate" value="0.0033"/>
|
|
<parameter constant="true" id="ka_r" metaid="iBioSim36" name="Reverse activation binding rate" value="1"/>
|
|
<parameter constant="true" id="ko_f" metaid="iBioSim37" name="Forward RNAP binding rate" value="0.033"/>
|
|
<parameter constant="true" id="ko_r" metaid="iBioSim38" name="Reverse RNAP binding rate" value="1"/>
|
|
<parameter constant="true" id="kao_f" metaid="iBioSim39" name="Forward activated RNAP binding rate" value="1"/>
|
|
<parameter constant="true" id="kao_r" metaid="iBioSim40" name="Reverse activated RNAP binding rate" value="1"/>
|
|
<parameter constant="true" id="nc" metaid="iBioSim41" name="Stoichiometry of binding" value="2"/>
|
|
<parameter constant="true" id="nr" metaid="iBioSim42" name="Initial RNAP count" value="30"/>
|
|
<parameter constant="true" id="ko" metaid="iBioSim43" name="Open complex production rate" value="0.05"/>
|
|
<parameter constant="true" id="kb" metaid="iBioSim44" name="Basal production rate" value="0.0001"/>
|
|
<parameter constant="true" id="ng" metaid="iBioSim45" name="Initial promoter count" value="2"/>
|
|
<parameter constant="true" id="np" metaid="iBioSim46" name="Stoichiometry of production" value="10"/>
|
|
<parameter constant="true" id="ka" metaid="iBioSim47" name="Activated production rate" value="0.25"/>
|
|
</listOfParameters>
|
|
<listOfConstraints>
|
|
<constraint metaid="c0">
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<ci> F </ci>
|
|
<apply>
|
|
<leq/>
|
|
<csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> t </csymbol>
|
|
<cn type="integer"> 2100 </cn>
|
|
</apply>
|
|
<apply>
|
|
<and/>
|
|
<apply>
|
|
<gt/>
|
|
<ci> S2 </ci>
|
|
<cn type="integer"> 80 </cn>
|
|
</apply>
|
|
<apply>
|
|
<lt/>
|
|
<ci> S3 </ci>
|
|
<cn type="integer"> 20 </cn>
|
|
</apply>
|
|
</apply>
|
|
</apply>
|
|
</math>
|
|
</constraint>
|
|
</listOfConstraints>
|
|
<listOfReactions>
|
|
<reaction compartment="Cell" id="Degradation_S4" metaid="iBioSim48" reversible="false">
|
|
<listOfReactants>
|
|
<speciesReference constant="true" species="S4" stoichiometry="10"/>
|
|
</listOfReactants>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<times/>
|
|
<ci> kd </ci>
|
|
<ci> S4 </ci>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Degradation_S1" metaid="iBioSim49" reversible="false">
|
|
<listOfReactants>
|
|
<speciesReference constant="true" species="S1" stoichiometry="10"/>
|
|
</listOfReactants>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<times/>
|
|
<ci> kd </ci>
|
|
<ci> S1 </ci>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Degradation_Z" metaid="iBioSim53" reversible="false">
|
|
<listOfReactants>
|
|
<speciesReference constant="true" species="Z" stoichiometry="10"/>
|
|
</listOfReactants>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<times/>
|
|
<ci> kd </ci>
|
|
<ci> Z </ci>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Degradation_C" metaid="iBioSim54" reversible="false">
|
|
<listOfReactants>
|
|
<speciesReference constant="true" species="C" stoichiometry="10"/>
|
|
</listOfReactants>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<times/>
|
|
<ci> kd </ci>
|
|
<ci> C </ci>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Production_P10" metaid="iBioSim32" reversible="false" sboTerm="SBO:0000589">
|
|
<listOfProducts>
|
|
<speciesReference constant="true" species="S4" stoichiometry="10"/>
|
|
</listOfProducts>
|
|
<listOfModifiers>
|
|
<modifierSpeciesReference sboTerm="SBO:0000598" species="P10"/>
|
|
<modifierSpeciesReference sboTerm="SBO:0000020" species="S2"/>
|
|
</listOfModifiers>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<divide/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<ci> P10 </ci>
|
|
<ci> ko </ci>
|
|
</apply>
|
|
<apply>
|
|
<divide/>
|
|
<ci> ko_f </ci>
|
|
<ci> ko_r </ci>
|
|
</apply>
|
|
</apply>
|
|
<ci> nr </ci>
|
|
</apply>
|
|
<apply>
|
|
<plus/>
|
|
<apply>
|
|
<plus/>
|
|
<cn type="integer"> 1 </cn>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<divide/>
|
|
<ci> ko_f </ci>
|
|
<ci> ko_r </ci>
|
|
</apply>
|
|
<ci> nr </ci>
|
|
</apply>
|
|
</apply>
|
|
<apply>
|
|
<power/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<divide/>
|
|
<ci> kr_f </ci>
|
|
<ci> kr_r </ci>
|
|
</apply>
|
|
<ci> S2 </ci>
|
|
</apply>
|
|
<ci> nc </ci>
|
|
</apply>
|
|
</apply>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Production_P1" metaid="iBioSim15" reversible="false" sboTerm="SBO:0000589">
|
|
<listOfProducts>
|
|
<speciesReference constant="true" species="S4" stoichiometry="10"/>
|
|
<speciesReference constant="true" species="X" stoichiometry="10"/>
|
|
</listOfProducts>
|
|
<listOfModifiers>
|
|
<modifierSpeciesReference sboTerm="SBO:0000598" species="P1"/>
|
|
<modifierSpeciesReference sboTerm="SBO:0000020" species="A"/>
|
|
</listOfModifiers>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<divide/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<ci> P1 </ci>
|
|
<ci> ko </ci>
|
|
</apply>
|
|
<apply>
|
|
<divide/>
|
|
<ci> ko_f </ci>
|
|
<ci> ko_r </ci>
|
|
</apply>
|
|
</apply>
|
|
<ci> nr </ci>
|
|
</apply>
|
|
<apply>
|
|
<plus/>
|
|
<apply>
|
|
<plus/>
|
|
<cn type="integer"> 1 </cn>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<divide/>
|
|
<ci> ko_f </ci>
|
|
<ci> ko_r </ci>
|
|
</apply>
|
|
<ci> nr </ci>
|
|
</apply>
|
|
</apply>
|
|
<apply>
|
|
<power/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<divide/>
|
|
<ci> kr_f </ci>
|
|
<ci> kr_r </ci>
|
|
</apply>
|
|
<ci> A </ci>
|
|
</apply>
|
|
<ci> nc </ci>
|
|
</apply>
|
|
</apply>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Production_P2" metaid="iBioSim17" reversible="false" sboTerm="SBO:0000589">
|
|
<listOfProducts>
|
|
<speciesReference constant="true" species="S4" stoichiometry="10"/>
|
|
<speciesReference constant="true" species="Y" stoichiometry="10"/>
|
|
</listOfProducts>
|
|
<listOfModifiers>
|
|
<modifierSpeciesReference sboTerm="SBO:0000598" species="P2"/>
|
|
<modifierSpeciesReference sboTerm="SBO:0000020" species="B"/>
|
|
</listOfModifiers>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<divide/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<ci> P2 </ci>
|
|
<ci> ko </ci>
|
|
</apply>
|
|
<apply>
|
|
<divide/>
|
|
<ci> ko_f </ci>
|
|
<ci> ko_r </ci>
|
|
</apply>
|
|
</apply>
|
|
<ci> nr </ci>
|
|
</apply>
|
|
<apply>
|
|
<plus/>
|
|
<apply>
|
|
<plus/>
|
|
<cn type="integer"> 1 </cn>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<divide/>
|
|
<ci> ko_f </ci>
|
|
<ci> ko_r </ci>
|
|
</apply>
|
|
<ci> nr </ci>
|
|
</apply>
|
|
</apply>
|
|
<apply>
|
|
<power/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<divide/>
|
|
<ci> kr_f </ci>
|
|
<ci> kr_r </ci>
|
|
</apply>
|
|
<ci> B </ci>
|
|
</apply>
|
|
<ci> nc </ci>
|
|
</apply>
|
|
</apply>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Production_P3" metaid="iBioSim19" reversible="false" sboTerm="SBO:0000589">
|
|
<listOfProducts>
|
|
<speciesReference constant="true" species="S3" stoichiometry="10"/>
|
|
<speciesReference constant="true" species="Z" stoichiometry="10"/>
|
|
</listOfProducts>
|
|
<listOfModifiers>
|
|
<modifierSpeciesReference sboTerm="SBO:0000598" species="P3"/>
|
|
<modifierSpeciesReference sboTerm="SBO:0000020" species="S4"/>
|
|
</listOfModifiers>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<divide/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<ci> P3 </ci>
|
|
<ci> ko </ci>
|
|
</apply>
|
|
<apply>
|
|
<divide/>
|
|
<ci> ko_f </ci>
|
|
<ci> ko_r </ci>
|
|
</apply>
|
|
</apply>
|
|
<ci> nr </ci>
|
|
</apply>
|
|
<apply>
|
|
<plus/>
|
|
<apply>
|
|
<plus/>
|
|
<cn type="integer"> 1 </cn>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<divide/>
|
|
<ci> ko_f </ci>
|
|
<ci> ko_r </ci>
|
|
</apply>
|
|
<ci> nr </ci>
|
|
</apply>
|
|
</apply>
|
|
<apply>
|
|
<power/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<divide/>
|
|
<ci> kr_f </ci>
|
|
<ci> kr_r </ci>
|
|
</apply>
|
|
<ci> S4 </ci>
|
|
</apply>
|
|
<ci> nc </ci>
|
|
</apply>
|
|
</apply>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Production_P4" metaid="iBioSim21" reversible="false" sboTerm="SBO:0000589">
|
|
<listOfProducts>
|
|
<speciesReference constant="true" species="S1" stoichiometry="10"/>
|
|
</listOfProducts>
|
|
<listOfModifiers>
|
|
<modifierSpeciesReference sboTerm="SBO:0000598" species="P4"/>
|
|
<modifierSpeciesReference sboTerm="SBO:0000020" species="X"/>
|
|
</listOfModifiers>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<divide/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<ci> P4 </ci>
|
|
<ci> ko </ci>
|
|
</apply>
|
|
<apply>
|
|
<divide/>
|
|
<ci> ko_f </ci>
|
|
<ci> ko_r </ci>
|
|
</apply>
|
|
</apply>
|
|
<ci> nr </ci>
|
|
</apply>
|
|
<apply>
|
|
<plus/>
|
|
<apply>
|
|
<plus/>
|
|
<cn type="integer"> 1 </cn>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<divide/>
|
|
<ci> ko_f </ci>
|
|
<ci> ko_r </ci>
|
|
</apply>
|
|
<ci> nr </ci>
|
|
</apply>
|
|
</apply>
|
|
<apply>
|
|
<power/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<divide/>
|
|
<ci> kr_f </ci>
|
|
<ci> kr_r </ci>
|
|
</apply>
|
|
<ci> X </ci>
|
|
</apply>
|
|
<ci> nc </ci>
|
|
</apply>
|
|
</apply>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Production_P5" metaid="iBioSim23" reversible="false" sboTerm="SBO:0000589">
|
|
<listOfProducts>
|
|
<speciesReference constant="true" species="S2" stoichiometry="10"/>
|
|
</listOfProducts>
|
|
<listOfModifiers>
|
|
<modifierSpeciesReference sboTerm="SBO:0000598" species="P5"/>
|
|
<modifierSpeciesReference sboTerm="SBO:0000020" species="S1"/>
|
|
</listOfModifiers>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<divide/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<ci> P5 </ci>
|
|
<ci> ko </ci>
|
|
</apply>
|
|
<apply>
|
|
<divide/>
|
|
<ci> ko_f </ci>
|
|
<ci> ko_r </ci>
|
|
</apply>
|
|
</apply>
|
|
<ci> nr </ci>
|
|
</apply>
|
|
<apply>
|
|
<plus/>
|
|
<apply>
|
|
<plus/>
|
|
<cn type="integer"> 1 </cn>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<divide/>
|
|
<ci> ko_f </ci>
|
|
<ci> ko_r </ci>
|
|
</apply>
|
|
<ci> nr </ci>
|
|
</apply>
|
|
</apply>
|
|
<apply>
|
|
<power/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<divide/>
|
|
<ci> kr_f </ci>
|
|
<ci> kr_r </ci>
|
|
</apply>
|
|
<ci> S1 </ci>
|
|
</apply>
|
|
<ci> nc </ci>
|
|
</apply>
|
|
</apply>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Production_P6" metaid="iBioSim25" reversible="false" sboTerm="SBO:0000589">
|
|
<listOfProducts>
|
|
<speciesReference constant="true" species="S3" stoichiometry="10"/>
|
|
</listOfProducts>
|
|
<listOfModifiers>
|
|
<modifierSpeciesReference sboTerm="SBO:0000598" species="P6"/>
|
|
<modifierSpeciesReference sboTerm="SBO:0000020" species="S2"/>
|
|
</listOfModifiers>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<divide/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<ci> P6 </ci>
|
|
<ci> ko </ci>
|
|
</apply>
|
|
<apply>
|
|
<divide/>
|
|
<ci> ko_f </ci>
|
|
<ci> ko_r </ci>
|
|
</apply>
|
|
</apply>
|
|
<ci> nr </ci>
|
|
</apply>
|
|
<apply>
|
|
<plus/>
|
|
<apply>
|
|
<plus/>
|
|
<cn type="integer"> 1 </cn>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<divide/>
|
|
<ci> ko_f </ci>
|
|
<ci> ko_r </ci>
|
|
</apply>
|
|
<ci> nr </ci>
|
|
</apply>
|
|
</apply>
|
|
<apply>
|
|
<power/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<divide/>
|
|
<ci> kr_f </ci>
|
|
<ci> kr_r </ci>
|
|
</apply>
|
|
<ci> S2 </ci>
|
|
</apply>
|
|
<ci> nc </ci>
|
|
</apply>
|
|
</apply>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Production_P7" metaid="iBioSim27" reversible="false" sboTerm="SBO:0000589">
|
|
<listOfProducts>
|
|
<speciesReference constant="true" species="S1" stoichiometry="10"/>
|
|
</listOfProducts>
|
|
<listOfModifiers>
|
|
<modifierSpeciesReference sboTerm="SBO:0000598" species="P7"/>
|
|
<modifierSpeciesReference sboTerm="SBO:0000020" species="Y"/>
|
|
</listOfModifiers>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<divide/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<ci> P7 </ci>
|
|
<ci> ko </ci>
|
|
</apply>
|
|
<apply>
|
|
<divide/>
|
|
<ci> ko_f </ci>
|
|
<ci> ko_r </ci>
|
|
</apply>
|
|
</apply>
|
|
<ci> nr </ci>
|
|
</apply>
|
|
<apply>
|
|
<plus/>
|
|
<apply>
|
|
<plus/>
|
|
<cn type="integer"> 1 </cn>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<divide/>
|
|
<ci> ko_f </ci>
|
|
<ci> ko_r </ci>
|
|
</apply>
|
|
<ci> nr </ci>
|
|
</apply>
|
|
</apply>
|
|
<apply>
|
|
<power/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<divide/>
|
|
<ci> kr_f </ci>
|
|
<ci> kr_r </ci>
|
|
</apply>
|
|
<ci> Y </ci>
|
|
</apply>
|
|
<ci> nc </ci>
|
|
</apply>
|
|
</apply>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Production_P8" metaid="iBioSim29" reversible="false" sboTerm="SBO:0000589">
|
|
<listOfProducts>
|
|
<speciesReference constant="true" species="S2" stoichiometry="10"/>
|
|
<speciesReference constant="true" species="Z" stoichiometry="10"/>
|
|
</listOfProducts>
|
|
<listOfModifiers>
|
|
<modifierSpeciesReference sboTerm="SBO:0000598" species="P8"/>
|
|
<modifierSpeciesReference sboTerm="SBO:0000020" species="S3"/>
|
|
</listOfModifiers>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<divide/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<ci> P8 </ci>
|
|
<ci> ko </ci>
|
|
</apply>
|
|
<apply>
|
|
<divide/>
|
|
<ci> ko_f </ci>
|
|
<ci> ko_r </ci>
|
|
</apply>
|
|
</apply>
|
|
<ci> nr </ci>
|
|
</apply>
|
|
<apply>
|
|
<plus/>
|
|
<apply>
|
|
<plus/>
|
|
<cn type="integer"> 1 </cn>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<divide/>
|
|
<ci> ko_f </ci>
|
|
<ci> ko_r </ci>
|
|
</apply>
|
|
<ci> nr </ci>
|
|
</apply>
|
|
</apply>
|
|
<apply>
|
|
<power/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<divide/>
|
|
<ci> kr_f </ci>
|
|
<ci> kr_r </ci>
|
|
</apply>
|
|
<ci> S3 </ci>
|
|
</apply>
|
|
<ci> nc </ci>
|
|
</apply>
|
|
</apply>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Production_P9" metaid="iBioSim31" reversible="false" sboTerm="SBO:0000589">
|
|
<listOfProducts>
|
|
<speciesReference constant="true" species="C" stoichiometry="10"/>
|
|
</listOfProducts>
|
|
<listOfModifiers>
|
|
<modifierSpeciesReference sboTerm="SBO:0000598" species="P9"/>
|
|
<modifierSpeciesReference sboTerm="SBO:0000020" species="Z"/>
|
|
</listOfModifiers>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<divide/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<times/>
|
|
<ci> P9 </ci>
|
|
<ci> ko </ci>
|
|
</apply>
|
|
<apply>
|
|
<divide/>
|
|
<ci> ko_f </ci>
|
|
<ci> ko_r </ci>
|
|
</apply>
|
|
</apply>
|
|
<ci> nr </ci>
|
|
</apply>
|
|
<apply>
|
|
<plus/>
|
|
<apply>
|
|
<plus/>
|
|
<cn type="integer"> 1 </cn>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<divide/>
|
|
<ci> ko_f </ci>
|
|
<ci> ko_r </ci>
|
|
</apply>
|
|
<ci> nr </ci>
|
|
</apply>
|
|
</apply>
|
|
<apply>
|
|
<power/>
|
|
<apply>
|
|
<times/>
|
|
<apply>
|
|
<divide/>
|
|
<ci> kr_f </ci>
|
|
<ci> kr_r </ci>
|
|
</apply>
|
|
<ci> Z </ci>
|
|
</apply>
|
|
<ci> nc </ci>
|
|
</apply>
|
|
</apply>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Degradation_X" metaid="iBioSim55" reversible="false">
|
|
<listOfReactants>
|
|
<speciesReference constant="true" species="X" stoichiometry="10"/>
|
|
</listOfReactants>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<times/>
|
|
<ci> kd </ci>
|
|
<ci> X </ci>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Degradation_S2" metaid="iBioSim50" reversible="false">
|
|
<listOfReactants>
|
|
<speciesReference constant="true" species="S2" stoichiometry="10"/>
|
|
</listOfReactants>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<times/>
|
|
<ci> kd </ci>
|
|
<ci> S2 </ci>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Degradation_S3" metaid="iBioSim51" reversible="false">
|
|
<listOfReactants>
|
|
<speciesReference constant="true" species="S3" stoichiometry="10"/>
|
|
</listOfReactants>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<times/>
|
|
<ci> kd </ci>
|
|
<ci> S3 </ci>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
<reaction compartment="Cell" id="Degradation_Y" metaid="iBioSim52" reversible="false">
|
|
<listOfReactants>
|
|
<speciesReference constant="true" species="Y" stoichiometry="10"/>
|
|
</listOfReactants>
|
|
<kineticLaw>
|
|
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
|
<apply>
|
|
<times/>
|
|
<ci> kd </ci>
|
|
<ci> Y </ci>
|
|
</apply>
|
|
</math>
|
|
</kineticLaw>
|
|
</reaction>
|
|
</listOfReactions>
|
|
</model>
|
|
</sbml>
|