Updated tutorial for synthetic biology focus using Genetic Toggle Switch example.

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cjmyers 2014-09-11 03:35:29 +00:00
parent 0a8a2c8bad
commit 289d8c2142
687 changed files with 40776 additions and 0 deletions

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<fbc:fluxBound fbc:reaction="R23" fbc:value="-1000" fbc:operation="greaterEqual" fbc:id="c44"/>
<fbc:fluxBound fbc:reaction="R23" fbc:value="1000" fbc:operation="lessEqual" fbc:id="c45"/>
<fbc:fluxBound fbc:reaction="R22" fbc:value="0" fbc:operation="greaterEqual" fbc:id="c46"/>
<fbc:fluxBound fbc:reaction="R22" fbc:value="1000" fbc:operation="lessEqual" fbc:id="c47"/>
<fbc:fluxBound fbc:reaction="R21" fbc:value="-1000" fbc:operation="greaterEqual" fbc:id="c48"/>
<fbc:fluxBound fbc:reaction="R21" fbc:value="1000" fbc:operation="lessEqual" fbc:id="c49"/>
<fbc:fluxBound fbc:reaction="R20" fbc:value="-1000" fbc:operation="greaterEqual" fbc:id="c50"/>
<fbc:fluxBound fbc:reaction="R20" fbc:value="1000" fbc:operation="lessEqual" fbc:id="c51"/>
</fbc:listOfFluxBounds>
<fbc:listOfObjectives xmlns:fbc="http://www.sbml.org/sbml/level3/version1/fbc/version1" fbc:activeObjective="OBJF">
<fbc:objective fbc:type="maximize" fbc:id="OBJF">
<fbc:listOfFluxObjectives>
<fbc:fluxObjective fbc:reaction="R26" fbc:coefficient="1"/>
</fbc:listOfFluxObjectives>
</fbc:objective>
</fbc:listOfObjectives>
<listOfUnitDefinitions>
<unitDefinition id="substance" name="substance">
<listOfUnits>
<unit scale="0" exponent="1" multiplier="1" kind="mole"/>
</listOfUnits>
</unitDefinition>
<unitDefinition id="area" name="area">
<listOfUnits>
<unit scale="0" exponent="2" multiplier="1" kind="metre"/>
</listOfUnits>
</unitDefinition>
<unitDefinition id="volume" name="volume">
<listOfUnits>
<unit scale="0" exponent="1" multiplier="1" kind="litre"/>
</listOfUnits>
</unitDefinition>
<unitDefinition id="length" name="length">
<listOfUnits>
<unit scale="0" exponent="1" multiplier="1" kind="metre"/>
</listOfUnits>
</unitDefinition>
<unitDefinition id="time" name="time">
<listOfUnits>
<unit scale="0" exponent="1" multiplier="1" kind="second"/>
</listOfUnits>
</unitDefinition>
<unitDefinition id="mmol_per_gDW_per_hr" name="mmol_per_gDW_per_hr">
<listOfUnits>
<unit scale="-3" exponent="1" multiplier="1" kind="mole"/>
<unit scale="0" exponent="-1" multiplier="1" kind="gram"/>
<unit scale="0" exponent="-1" multiplier="0.00027777" kind="second"/>
</listOfUnits>
</unitDefinition>
</listOfUnitDefinitions>
<listOfCompartments>
<compartment id="Cell" constant="false" name="Cell" size="1"/>
</listOfCompartments>
<listOfSpecies>
<species id="A" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="A" metaid="meta_A" boundaryCondition="false" compartment="Cell"/>
<species id="B" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="B" metaid="meta_B" boundaryCondition="false" compartment="Cell"/>
<species id="C" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="C" metaid="meta_C" boundaryCondition="false" compartment="Cell"/>
<species id="D" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="D" metaid="meta_D" boundaryCondition="false" compartment="Cell"/>
<species id="E" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="E" metaid="meta_E" boundaryCondition="false" compartment="Cell"/>
<species id="F" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="F" metaid="meta_F" boundaryCondition="false" compartment="Cell"/>
<species id="G" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="G" metaid="meta_G" boundaryCondition="false" compartment="Cell"/>
<species id="H" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="H" metaid="meta_H" boundaryCondition="false" compartment="Cell"/>
<species id="I" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="I" metaid="meta_I" boundaryCondition="false" compartment="Cell"/>
<species id="J" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="J" metaid="meta_J" boundaryCondition="false" compartment="Cell"/>
<species id="K" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="K" metaid="meta_K" boundaryCondition="false" compartment="Cell"/>
<species id="L" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="L" metaid="meta_L" boundaryCondition="false" compartment="Cell"/>
<species id="M" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="M" metaid="meta_M" boundaryCondition="false" compartment="Cell"/>
<species id="N" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="N" metaid="meta_N" boundaryCondition="false" compartment="Cell"/>
<species id="O" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="O" metaid="meta_O" boundaryCondition="false" compartment="Cell"/>
<species id="P" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="P" metaid="meta_P" boundaryCondition="false" compartment="Cell"/>
<species id="Q" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="Q" metaid="meta_Q" boundaryCondition="false" compartment="Cell"/>
<species id="R" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="R" metaid="meta_R" boundaryCondition="false" compartment="Cell"/>
<species id="S" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="S" metaid="meta_S" boundaryCondition="false" compartment="Cell"/>
<species id="T" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="T" metaid="meta_T" boundaryCondition="true" compartment="Cell"/>
<species id="U" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="U" metaid="meta_U" boundaryCondition="true" compartment="Cell"/>
<species id="X" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="X" metaid="meta_X" boundaryCondition="true" compartment="Cell"/>
<species id="Y" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="Y" metaid="meta_Y" boundaryCondition="true" compartment="Cell"/>
</listOfSpecies>
<listOfReactions>
<reaction id="R16" name="R16" metaid="meta_R16" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="J" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="M" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R14" name="R14" metaid="meta_R14" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="K" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="L" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R15" name="R15" metaid="meta_R15" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="L" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="Q" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R12" name="R12" metaid="meta_R12" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="I" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="J" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R07" name="R07" metaid="meta_R07" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="E" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="F" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R13" name="R13" metaid="meta_R13" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="J" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="K" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R01" name="R01" metaid="meta_R01" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="X" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="A" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R17" name="R17" metaid="meta_R17" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="M" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="N" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R03" name="R03" metaid="meta_R03" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C1</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C1"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="A" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="C" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R02" name="R02" metaid="meta_R02" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C1</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C1"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="A" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="B" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R05" name="R05" metaid="meta_R05" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="B" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="D" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R04" name="R04" metaid="meta_R04" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C1</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C1"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="C" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="B" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R10" name="R10" metaid="meta_R10" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="G" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="H" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R06" name="R06" metaid="meta_R06" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="D" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="E" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R09" name="R09" metaid="meta_R09" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="D" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="G" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R08" name="R08" metaid="meta_R08" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="F" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="I" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R11" name="R11" metaid="meta_R11" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="H" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="I" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R18" name="R18" metaid="meta_R18" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="N" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="Q" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R19" name="R19" metaid="meta_R19" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="K" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="O" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R26" name="R26" metaid="meta_R26" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="S" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="Y" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R25" name="R25" metaid="meta_R25" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="A" stoichiometry="1"/>
<speciesReference constant="false" species="T" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="S" stoichiometry="0.5"/>
<speciesReference constant="false" species="U" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R24" name="R24" metaid="meta_R24" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C4</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C4"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="R" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="S" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R23" name="R23" metaid="meta_R23" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C4</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C4"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="R" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="S" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R22" name="R22" metaid="meta_R22" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="Q" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="R" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R21" name="R21" metaid="meta_R21" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="P" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="L" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R20" name="R20" metaid="meta_R20" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="O" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="P" stoichiometry="1"/>
</listOfProducts>
</reaction>
</listOfReactions>
</model>
</sbml>

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@ -0,0 +1,21 @@
#Probability Data
#Mon Oct 28 15:15:03 MDT 2013
visibleLegend=true
gradient=false
species.number.1=1
species.number.0=0
species.paint.1=Blue
species.directory.1=
species.paint.0=Red
x.axis=
species.directory.0=
shadow=false
y.axis=Percent
plot.range.grid.line.paint=-4144960
chart.background.paint=-1118482
species.name.1=R01
species.id.1=R01
species.name.0=Objective
species.id.0=Objective
plot.background.paint=-1
title=MODEL_01186 simulation results

View file

@ -0,0 +1,27 @@
#MODEL_01186 Properties
#Mon Oct 28 15:15:03 MDT 2013
reb2sac.operator.max.concentration.threshold=15
reb2sac.qssa.condition.1=0.1
monte.carlo.simulation.time.step=inf
monte.carlo.simulation.print.interval=1.0
monte.carlo.simulation.runs=1
reb2sac.simulation.method=FBA
ode.simulation.time.limit=100.0
simulation.run.termination.decider=constraint
reb2sac.generate.statistics=false
monte.carlo.simulation.random.seed=314159
ode.simulation.time.step=inf
ode.simulation.out.dir=.
monte.carlo.simulation.time.limit=100.0
simulation.printer.tracking.quantity=amount
simulation.printer=tsd.printer
monte.carlo.simulation.min.time.step=0.0
ode.simulation.absolute.error=1.0E-4
ode.simulation.print.interval=1.0
ode.simulation.min.time.step=0.0
reb2sac.abstraction.method=none
reb2sac.rapid.equilibrium.condition.2=0.1
reb2sac.diffusion.stoichiometry.amplification.value=1.0
reb2sac.rapid.equilibrium.condition.1=0.1
monte.carlo.simulation.out.dir=.
selected.simulator=rkf45

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@ -0,0 +1,2 @@
MODEL_01186.xml

View file

@ -0,0 +1,673 @@
<?xml version='1.0' encoding='UTF-8' standalone='no'?>
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<model id="MODEL_01186" name="Created by iBioSim flatten routine" metaid="meta_MODEL_01186" substanceUnits="mole" volumeUnits="litre">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p> <html:span style="font-family: Courier New,Courier,monospace;">Maximize single objective function, hard bounds.</html:span>
</html:p>
</body>
</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#meta_MODEL_01186">
<dc:creator>
<rdf:Bag>
<rdf:li rdf:parseType="Resource">
<vCard:N rdf:parseType="Resource">
<vCard:Family>Olivier</vCard:Family>
<vCard:Given>Brett</vCard:Given>
</vCard:N>
<vCard:EMAIL>bgoli@users.sourceforge.net</vCard:EMAIL>
<vCard:ORG rdf:parseType="Resource">
<vCard:Orgname>VU university Amsterdam</vCard:Orgname>
</vCard:ORG>
</rdf:li>
</rdf:Bag>
</dc:creator>
<dcterms:created rdf:parseType="Resource">
<dcterms:W3CDTF>2012-12-21T11:05:21Z</dcterms:W3CDTF>
</dcterms:created>
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<dcterms:W3CDTF>2012-12-21T10:05:21Z</dcterms:W3CDTF>
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<dcterms:modified rdf:parseType="Resource">
<dcterms:W3CDTF>2013-10-28T21:14:39Z</dcterms:W3CDTF>
</dcterms:modified>
<dcterms:modified rdf:parseType="Resource">
<dcterms:W3CDTF>2013-10-28T21:14:52Z</dcterms:W3CDTF>
</dcterms:modified>
<dcterms:modified rdf:parseType="Resource">
<dcterms:W3CDTF>2013-10-28T21:14:53Z</dcterms:W3CDTF>
</dcterms:modified>
</rdf:Description>
</rdf:RDF>
</annotation>
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<unitDefinition id="area" name="area">
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<unit scale="0" exponent="2" multiplier="1" kind="metre"/>
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<unitDefinition id="volume" name="volume">
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<unit scale="0" exponent="1" multiplier="1" kind="litre"/>
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<unitDefinition id="length" name="length">
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<unitDefinition id="mmol_per_gDW_per_hr" name="mmol_per_gDW_per_hr">
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<unit scale="0" exponent="-1" multiplier="0.00027777" kind="second"/>
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</unitDefinition>
<unitDefinition id="u_1_second_n1">
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<listOfCompartments>
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<listOfSpecies>
<species id="A" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="A" metaid="meta_A" boundaryCondition="false" compartment="Cell"/>
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<reaction id="R05" name="R05" metaid="meta_R05" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="B" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="D" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R04" name="R04" metaid="meta_R04" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C1</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C1"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="C" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="B" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R10" name="R10" metaid="meta_R10" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="G" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="H" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R06" name="R06" metaid="meta_R06" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="D" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="E" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R09" name="R09" metaid="meta_R09" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="D" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="G" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R08" name="R08" metaid="meta_R08" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="F" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="I" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R11" name="R11" metaid="meta_R11" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="H" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="I" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R18" name="R18" metaid="meta_R18" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="N" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="Q" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R19" name="R19" metaid="meta_R19" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="K" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="O" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R26" name="R26" metaid="meta_R26" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="S" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="Y" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R25" name="R25" metaid="meta_R25" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="A" stoichiometry="1"/>
<speciesReference constant="false" species="T" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="S" stoichiometry="0.5"/>
<speciesReference constant="false" species="U" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R24" name="R24" metaid="meta_R24" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C4</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C4"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="R" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="S" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R23" name="R23" metaid="meta_R23" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C4</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C4"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="R" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="S" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R22" name="R22" metaid="meta_R22" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="Q" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="R" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R21" name="R21" metaid="meta_R21" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="P" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="L" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R20" name="R20" metaid="meta_R20" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="O" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="P" stoichiometry="1"/>
</listOfProducts>
</reaction>
</listOfReactions>
</model>
</sbml>

View file

@ -0,0 +1,3 @@
Total Simulation Time: 0.356126 seconds for MODEL_01186

View file

@ -0,0 +1,2 @@
#total Objective R19 R17 R18 R15 R16 R13 R14 R11 R12 R10 R26 R25 R24 R23 R22 R21 R20 R06 R07 R08 R09 R02 R03 R04 R05 R01
100 1.0 0.0996 0.6016 0.6016 0.3984 0.6016 0.3984 0.2988 0.5 1.0 0.5 1.0 0.0 260.8256 -259.8256 1.0 0.0996 0.0996 0.5 0.5 0.5 0.5 0.6667 0.3333 0.3333 1.0 1.0

View file

@ -0,0 +1,658 @@
<?xml version='1.0' encoding='UTF-8' standalone='no'?>
<sbml xmlns="http://www.sbml.org/sbml/level3/version1/core" xmlns:html="http://www.w3.org/1999/xhtml" level="3" fbc:required="false" xmlns:fbc="http://www.sbml.org/sbml/level3/version1/fbc/version1" version="1">
<model id="MODEL_01187" metaid="meta_MODEL_01187">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p> <html:span style="font-family: Courier New,Courier,monospace;">Minimize single objective function, hard bounds.</html:span>
</html:p>
</body>
</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#meta_MODEL_01187">
<dc:creator>
<rdf:Bag>
<rdf:li rdf:parseType="Resource">
<vCard:N rdf:parseType="Resource">
<vCard:Family>Olivier</vCard:Family>
<vCard:Given>Brett</vCard:Given>
</vCard:N>
<vCard:EMAIL>bgoli@users.sourceforge.net</vCard:EMAIL>
<vCard:ORG rdf:parseType="Resource">
<vCard:Orgname>VU university Amsterdam</vCard:Orgname>
</vCard:ORG>
</rdf:li>
</rdf:Bag>
</dc:creator>
<dcterms:created rdf:parseType="Resource">
<dcterms:W3CDTF>2012-12-21T11:05:21Z</dcterms:W3CDTF>
</dcterms:created>
<dcterms:modified rdf:parseType="Resource">
<dcterms:W3CDTF>2012-12-21T10:05:21Z</dcterms:W3CDTF>
</dcterms:modified>
<dcterms:modified rdf:parseType="Resource">
<dcterms:W3CDTF>2013-10-25T22:25:29Z</dcterms:W3CDTF>
</dcterms:modified>
</rdf:Description>
</rdf:RDF>
</annotation>
<fbc:listOfFluxBounds xmlns:fbc="http://www.sbml.org/sbml/level3/version1/fbc/version1">
<fbc:fluxBound fbc:reaction="R16" fbc:value="0" fbc:operation="greaterEqual" fbc:id="c0"/>
<fbc:fluxBound fbc:reaction="R16" fbc:value="1000" fbc:operation="lessEqual" fbc:id="c1"/>
<fbc:fluxBound fbc:reaction="R03" fbc:value="-1000" fbc:operation="greaterEqual" fbc:id="c2"/>
<fbc:fluxBound fbc:reaction="R03" fbc:value="1000" fbc:operation="lessEqual" fbc:id="c3"/>
<fbc:fluxBound fbc:reaction="R02" fbc:value="-1000" fbc:operation="greaterEqual" fbc:id="c4"/>
<fbc:fluxBound fbc:reaction="R02" fbc:value="1000" fbc:operation="lessEqual" fbc:id="c5"/>
<fbc:fluxBound fbc:reaction="R05" fbc:value="0" fbc:operation="greaterEqual" fbc:id="c6"/>
<fbc:fluxBound fbc:reaction="R05" fbc:value="1000" fbc:operation="lessEqual" fbc:id="c7"/>
<fbc:fluxBound fbc:reaction="R07" fbc:value="0" fbc:operation="greaterEqual" fbc:id="c8"/>
<fbc:fluxBound fbc:reaction="R07" fbc:value="1000" fbc:operation="lessEqual" fbc:id="c9"/>
<fbc:fluxBound fbc:reaction="R04" fbc:value="-1000" fbc:operation="greaterEqual" fbc:id="c10"/>
<fbc:fluxBound fbc:reaction="R04" fbc:value="1000" fbc:operation="lessEqual" fbc:id="c11"/>
<fbc:fluxBound fbc:reaction="R01" fbc:value="0" fbc:operation="greaterEqual" fbc:id="c12"/>
<fbc:fluxBound fbc:reaction="R01" fbc:value="1" fbc:operation="lessEqual" fbc:id="c13"/>
<fbc:fluxBound fbc:reaction="R17" fbc:value="0" fbc:operation="greaterEqual" fbc:id="c14"/>
<fbc:fluxBound fbc:reaction="R17" fbc:value="1000" fbc:operation="lessEqual" fbc:id="c15"/>
<fbc:fluxBound fbc:reaction="R14" fbc:value="-1000" fbc:operation="greaterEqual" fbc:id="c16"/>
<fbc:fluxBound fbc:reaction="R14" fbc:value="1000" fbc:operation="lessEqual" fbc:id="c17"/>
<fbc:fluxBound fbc:reaction="R15" fbc:value="0" fbc:operation="greaterEqual" fbc:id="c18"/>
<fbc:fluxBound fbc:reaction="R15" fbc:value="1000" fbc:operation="lessEqual" fbc:id="c19"/>
<fbc:fluxBound fbc:reaction="R12" fbc:value="0" fbc:operation="greaterEqual" fbc:id="c20"/>
<fbc:fluxBound fbc:reaction="R12" fbc:value="1000" fbc:operation="lessEqual" fbc:id="c21"/>
<fbc:fluxBound fbc:reaction="R13" fbc:value="0" fbc:operation="greaterEqual" fbc:id="c22"/>
<fbc:fluxBound fbc:reaction="R13" fbc:value="1000" fbc:operation="lessEqual" fbc:id="c23"/>
<fbc:fluxBound fbc:reaction="R10" fbc:value="0" fbc:operation="greaterEqual" fbc:id="c24"/>
<fbc:fluxBound fbc:reaction="R10" fbc:value="1000" fbc:operation="lessEqual" fbc:id="c25"/>
<fbc:fluxBound fbc:reaction="R11" fbc:value="0" fbc:operation="greaterEqual" fbc:id="c26"/>
<fbc:fluxBound fbc:reaction="R11" fbc:value="1000" fbc:operation="lessEqual" fbc:id="c27"/>
<fbc:fluxBound fbc:reaction="R09" fbc:value="0" fbc:operation="greaterEqual" fbc:id="c28"/>
<fbc:fluxBound fbc:reaction="R09" fbc:value="1000" fbc:operation="lessEqual" fbc:id="c29"/>
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<fbc:fluxBound fbc:reaction="R20" fbc:value="1000" fbc:operation="lessEqual" fbc:id="c51"/>
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<fbc:listOfObjectives xmlns:fbc="http://www.sbml.org/sbml/level3/version1/fbc/version1" fbc:activeObjective="OBJF">
<fbc:objective fbc:type="minimize" fbc:id="OBJF"/>
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<unitDefinition id="substance" name="substance">
<listOfUnits>
<unit scale="0" exponent="1" multiplier="1" kind="mole"/>
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<unitDefinition id="area" name="area">
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<unit scale="0" exponent="2" multiplier="1" kind="metre"/>
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<unitDefinition id="volume" name="volume">
<listOfUnits>
<unit scale="0" exponent="1" multiplier="1" kind="litre"/>
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<unitDefinition id="length" name="length">
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<unitDefinition id="time" name="time">
<listOfUnits>
<unit scale="0" exponent="1" multiplier="1" kind="second"/>
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</unitDefinition>
<unitDefinition id="mmol_per_gDW_per_hr" name="mmol_per_gDW_per_hr">
<listOfUnits>
<unit scale="-3" exponent="1" multiplier="1" kind="mole"/>
<unit scale="0" exponent="-1" multiplier="1" kind="gram"/>
<unit scale="0" exponent="-1" multiplier="0.00027777" kind="second"/>
</listOfUnits>
</unitDefinition>
</listOfUnitDefinitions>
<listOfCompartments>
<compartment id="Cell" constant="false" name="Cell" size="1"/>
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<listOfSpecies>
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<species id="B" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="B" metaid="meta_B" boundaryCondition="false" compartment="Cell"/>
<species id="C" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="C" metaid="meta_C" boundaryCondition="false" compartment="Cell"/>
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<species id="E" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="E" metaid="meta_E" boundaryCondition="false" compartment="Cell"/>
<species id="F" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="F" metaid="meta_F" boundaryCondition="false" compartment="Cell"/>
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<species id="H" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="H" metaid="meta_H" boundaryCondition="false" compartment="Cell"/>
<species id="I" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="I" metaid="meta_I" boundaryCondition="false" compartment="Cell"/>
<species id="J" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="J" metaid="meta_J" boundaryCondition="false" compartment="Cell"/>
<species id="K" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="K" metaid="meta_K" boundaryCondition="false" compartment="Cell"/>
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<species id="N" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="N" metaid="meta_N" boundaryCondition="false" compartment="Cell"/>
<species id="O" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="O" metaid="meta_O" boundaryCondition="false" compartment="Cell"/>
<species id="P" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="P" metaid="meta_P" boundaryCondition="false" compartment="Cell"/>
<species id="Q" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="Q" metaid="meta_Q" boundaryCondition="false" compartment="Cell"/>
<species id="R" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="R" metaid="meta_R" boundaryCondition="false" compartment="Cell"/>
<species id="S" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="S" metaid="meta_S" boundaryCondition="false" compartment="Cell"/>
<species id="T" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="T" metaid="meta_T" boundaryCondition="true" compartment="Cell"/>
<species id="U" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="U" metaid="meta_U" boundaryCondition="true" compartment="Cell"/>
<species id="X" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="X" metaid="meta_X" boundaryCondition="true" compartment="Cell"/>
<species id="Y" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="Y" metaid="meta_Y" boundaryCondition="true" compartment="Cell"/>
</listOfSpecies>
<listOfReactions>
<reaction id="R16" name="R16" metaid="meta_R16" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
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</annotation>
<listOfReactants>
<speciesReference constant="false" species="J" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="M" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R14" name="R14" metaid="meta_R14" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
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<speciesReference constant="false" species="K" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="L" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R15" name="R15" metaid="meta_R15" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
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<listOfReactants>
<speciesReference constant="false" species="L" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="Q" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R12" name="R12" metaid="meta_R12" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
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</annotation>
<listOfReactants>
<speciesReference constant="false" species="I" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="J" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R07" name="R07" metaid="meta_R07" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
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</annotation>
<listOfReactants>
<speciesReference constant="false" species="E" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="F" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R13" name="R13" metaid="meta_R13" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
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</annotation>
<listOfReactants>
<speciesReference constant="false" species="J" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="K" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R01" name="R01" metaid="meta_R01" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
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</annotation>
<listOfReactants>
<speciesReference constant="false" species="X" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="A" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R17" name="R17" metaid="meta_R17" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
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</annotation>
<listOfReactants>
<speciesReference constant="false" species="M" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="N" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R03" name="R03" metaid="meta_R03" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C1</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C1"/>
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</annotation>
<listOfReactants>
<speciesReference constant="false" species="A" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="C" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R02" name="R02" metaid="meta_R02" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C1</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C1"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="A" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="B" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R05" name="R05" metaid="meta_R05" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="B" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="D" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R04" name="R04" metaid="meta_R04" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C1</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C1"/>
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</annotation>
<listOfReactants>
<speciesReference constant="false" species="C" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="B" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R10" name="R10" metaid="meta_R10" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="G" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="H" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R06" name="R06" metaid="meta_R06" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="D" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="E" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R09" name="R09" metaid="meta_R09" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="D" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="G" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R08" name="R08" metaid="meta_R08" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="F" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="I" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R11" name="R11" metaid="meta_R11" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="H" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="I" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R18" name="R18" metaid="meta_R18" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="N" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="Q" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R19" name="R19" metaid="meta_R19" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="K" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="O" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R26" name="R26" metaid="meta_R26" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="S" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="Y" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R25" name="R25" metaid="meta_R25" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
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<listOfReactants>
<speciesReference constant="false" species="A" stoichiometry="1"/>
<speciesReference constant="false" species="T" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="S" stoichiometry="0.5"/>
<speciesReference constant="false" species="U" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R24" name="R24" metaid="meta_R24" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C4</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C4"/>
</listOfKeyValueData>
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<listOfReactants>
<speciesReference constant="false" species="R" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="S" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R23" name="R23" metaid="meta_R23" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C4</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C4"/>
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<listOfReactants>
<speciesReference constant="false" species="R" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="S" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R22" name="R22" metaid="meta_R22" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
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<listOfReactants>
<speciesReference constant="false" species="Q" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="R" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R21" name="R21" metaid="meta_R21" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
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<listOfReactants>
<speciesReference constant="false" species="P" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="L" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R20" name="R20" metaid="meta_R20" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
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</annotation>
<listOfReactants>
<speciesReference constant="false" species="O" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="P" stoichiometry="1"/>
</listOfProducts>
</reaction>
</listOfReactions>
</model>
</sbml>

View file

@ -0,0 +1,19 @@
#Graph Data
#Fri Oct 25 16:20:04 MDT 2013
visibleLegend=true
x.axis=time
auto.resize=true
y.max=
plot.domain.grid.line.paint=-4144960
x.max=
plot.background.paint=-1
y.axis=amount
chart.background.paint=-1118482
x.scale=
LogY=false
LogX=false
title=MODEL_01187 simulation results
plot.range.grid.line.paint=-4144960
y.min=
y.scale=
x.min=

View file

@ -0,0 +1,26 @@
#Probability Data
#Fri Oct 25 16:20:04 MDT 2013
visibleLegend=true
gradient=false
species.number.2=2
species.number.1=1
species.number.0=0
species.paint.2=Green
species.directory.2=
species.paint.1=Blue
species.directory.1=
species.paint.0=Red
x.axis=
species.directory.0=
shadow=false
y.axis=Percent
plot.range.grid.line.paint=-4144960
chart.background.paint=-1118482
species.id.2=R02
species.name.2=R02
species.name.1=R01
species.id.1=R01
species.name.0=Objective
species.id.0=Objective
plot.background.paint=-1
title=MODEL_01187 simulation results

View file

@ -0,0 +1,27 @@
#MODEL_01187 Properties
#Fri Oct 25 16:20:04 MDT 2013
reb2sac.operator.max.concentration.threshold=15
reb2sac.qssa.condition.1=0.1
monte.carlo.simulation.time.step=inf
monte.carlo.simulation.print.interval=1.0
monte.carlo.simulation.runs=1
reb2sac.simulation.method=FBA
ode.simulation.time.limit=100.0
simulation.run.termination.decider=constraint
reb2sac.generate.statistics=false
monte.carlo.simulation.random.seed=314159
ode.simulation.time.step=inf
ode.simulation.out.dir=.
monte.carlo.simulation.time.limit=100.0
simulation.printer.tracking.quantity=amount
simulation.printer=tsd.printer
monte.carlo.simulation.min.time.step=0.0
ode.simulation.absolute.error=1.0E-4
ode.simulation.print.interval=1.0
ode.simulation.min.time.step=0.0
reb2sac.abstraction.method=none
reb2sac.rapid.equilibrium.condition.2=0.1
reb2sac.diffusion.stoichiometry.amplification.value=1.0
reb2sac.rapid.equilibrium.condition.1=0.1
monte.carlo.simulation.out.dir=.
selected.simulator=rkf45

View file

@ -0,0 +1,2 @@
MODEL_01187.xml

View file

@ -0,0 +1,669 @@
<?xml version='1.0' encoding='UTF-8' standalone='no'?>
<sbml xmlns="http://www.sbml.org/sbml/level3/version1/core" xmlns:html="http://www.w3.org/1999/xhtml" level="3" fbc:required="false" xmlns:fbc="http://www.sbml.org/sbml/level3/version1/fbc/version1" version="1">
<model id="MODEL_01187" name="Created by iBioSim flatten routine" metaid="meta_MODEL_01187" substanceUnits="mole" volumeUnits="litre">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p> <html:span style="font-family: Courier New,Courier,monospace;">Minimize single objective function, hard bounds.</html:span>
</html:p>
</body>
</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#meta_MODEL_01187">
<dc:creator>
<rdf:Bag>
<rdf:li rdf:parseType="Resource">
<vCard:N rdf:parseType="Resource">
<vCard:Family>Olivier</vCard:Family>
<vCard:Given>Brett</vCard:Given>
</vCard:N>
<vCard:EMAIL>bgoli@users.sourceforge.net</vCard:EMAIL>
<vCard:ORG rdf:parseType="Resource">
<vCard:Orgname>VU university Amsterdam</vCard:Orgname>
</vCard:ORG>
</rdf:li>
</rdf:Bag>
</dc:creator>
<dcterms:created rdf:parseType="Resource">
<dcterms:W3CDTF>2012-12-21T11:05:21Z</dcterms:W3CDTF>
</dcterms:created>
<dcterms:modified rdf:parseType="Resource">
<dcterms:W3CDTF>2012-12-21T10:05:21Z</dcterms:W3CDTF>
</dcterms:modified>
<dcterms:modified rdf:parseType="Resource">
<dcterms:W3CDTF>2013-10-25T22:18:57Z</dcterms:W3CDTF>
</dcterms:modified>
<dcterms:modified rdf:parseType="Resource">
<dcterms:W3CDTF>2013-10-25T22:19:14Z</dcterms:W3CDTF>
</dcterms:modified>
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<dcterms:W3CDTF>2013-10-25T22:19:17Z</dcterms:W3CDTF>
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<speciesReference constant="false" species="N" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="Q" stoichiometry="1"/>
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</reaction>
<reaction id="R19" name="R19" metaid="meta_R19" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
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</annotation>
<listOfReactants>
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</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="O" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R26" name="R26" metaid="meta_R26" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
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</annotation>
<listOfReactants>
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</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="Y" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R25" name="R25" metaid="meta_R25" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
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</listOfKeyValueData>
</annotation>
<listOfReactants>
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<speciesReference constant="false" species="T" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
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<speciesReference constant="false" species="U" stoichiometry="1"/>
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</reaction>
<reaction id="R24" name="R24" metaid="meta_R24" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C4</html:p>
</body>
</notes>
<annotation>
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<listOfReactants>
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<listOfProducts>
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<reaction id="R23" name="R23" metaid="meta_R23" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C4</html:p>
</body>
</notes>
<annotation>
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<listOfReactants>
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<listOfProducts>
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</reaction>
<reaction id="R22" name="R22" metaid="meta_R22" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
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</annotation>
<listOfReactants>
<speciesReference constant="false" species="Q" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="R" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R21" name="R21" metaid="meta_R21" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
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</annotation>
<listOfReactants>
<speciesReference constant="false" species="P" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="L" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R20" name="R20" metaid="meta_R20" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="O" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="P" stoichiometry="1"/>
</listOfProducts>
</reaction>
</listOfReactions>
</model>
</sbml>

View file

@ -0,0 +1,3 @@
Total Simulation Time: 0.05902 seconds for MODEL_01187

View file

@ -0,0 +1 @@
[]

View file

@ -0,0 +1,2 @@
#total Objective R19 R17 R18 R15 R16 R13 R14 R11 R12 R10 R26 R25 R24 R23 R22 R21 R20 R06 R07 R08 R09 R02 R03 R04 R05 R01
100 0.0 0.0884 0.5343 0.5343 0.3534 0.5343 0.3534 0.2651 0.4439 0.8877 0.4439 0.9173 0.0591 260.798 -259.9103 0.8877 0.0884 0.0884 0.4439 0.4439 0.4439 0.4439 0.5918 0.2959 0.2959 0.8877 0.9469

View file

@ -0,0 +1,983 @@
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<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p> <html:span style="font-family: Courier New,Courier,monospace;">Infeasible solution, should return a nan</html:span>
</html:p>
</body>
</notes>
<annotation>
<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#">
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<dc:creator>
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<vCard:N rdf:parseType="Resource">
<vCard:Family>Olivier</vCard:Family>
<vCard:Given>Brett</vCard:Given>
</vCard:N>
<vCard:EMAIL>bgoli@users.sourceforge.net</vCard:EMAIL>
<vCard:ORG rdf:parseType="Resource">
<vCard:Orgname>VU university Amsterdam</vCard:Orgname>
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<dcterms:W3CDTF>2012-12-21T11:05:22Z</dcterms:W3CDTF>
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<dcterms:W3CDTF>2012-12-21T10:05:22Z</dcterms:W3CDTF>
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<dcterms:modified rdf:parseType="Resource">
<dcterms:W3CDTF>2013-10-31T23:16:18Z</dcterms:W3CDTF>
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<layout:boundingBox>
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<layout:textGlyph layout:graphicalObject="Glyph__E" layout:id="TextGlyph__E" layout:text="E">
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</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__G" layout:id="TextGlyph__G" layout:text="G">
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</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__H" layout:id="TextGlyph__H" layout:text="H">
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</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__I" layout:id="TextGlyph__I" layout:text="I">
<layout:boundingBox>
<layout:position layout:x="180" layout:y="360"/>
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</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__J" layout:id="TextGlyph__J" layout:text="J">
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</layout:textGlyph>
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</layout:textGlyph>
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</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__N" layout:id="TextGlyph__N" layout:text="N">
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</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__O" layout:id="TextGlyph__O" layout:text="O">
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</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__P" layout:id="TextGlyph__P" layout:text="P">
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</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__Q" layout:id="TextGlyph__Q" layout:text="Q">
<layout:boundingBox>
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</layout:boundingBox>
</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__R" layout:id="TextGlyph__R" layout:text="R">
<layout:boundingBox>
<layout:position layout:x="360" layout:y="320"/>
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</layout:boundingBox>
</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__S" layout:id="TextGlyph__S" layout:text="S">
<layout:boundingBox>
<layout:position layout:x="550" layout:y="380"/>
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</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__T" layout:id="TextGlyph__T" layout:text="T">
<layout:boundingBox>
<layout:position layout:x="400" layout:y="0"/>
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</layout:boundingBox>
</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__U" layout:id="TextGlyph__U" layout:text="U">
<layout:boundingBox>
<layout:position layout:x="420" layout:y="40"/>
<layout:dimensions layout:width="100" layout:height="30"/>
</layout:boundingBox>
</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__X" layout:id="TextGlyph__X" layout:text="X">
<layout:boundingBox>
<layout:position layout:x="440" layout:y="80"/>
<layout:dimensions layout:width="100" layout:height="30"/>
</layout:boundingBox>
</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__Y" layout:id="TextGlyph__Y" layout:text="Y">
<layout:boundingBox>
<layout:position layout:x="460" layout:y="120"/>
<layout:dimensions layout:width="100" layout:height="30"/>
</layout:boundingBox>
</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__R25" layout:id="TextGlyph__R25" layout:text="R25">
<layout:boundingBox>
<layout:position layout:x="480" layout:y="160"/>
<layout:dimensions layout:width="30" layout:height="30"/>
</layout:boundingBox>
</layout:textGlyph>
</layout:listOfTextGlyphs>
</layout:layout>
</layout:listOfLayouts>
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<listOfUnits>
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<listOfUnits>
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<listOfUnits>
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<unitDefinition id="length" name="length">
<listOfUnits>
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<listOfUnits>
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</unitDefinition>
<unitDefinition id="mmol_per_gDW_per_hr" name="mmol_per_gDW_per_hr">
<listOfUnits>
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<unit scale="0" exponent="-1" multiplier="1" kind="gram"/>
<unit scale="0" exponent="-1" multiplier="0.00027777" kind="second"/>
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</annotation>
</compartment>
</listOfCompartments>
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<species id="B" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="B" metaid="meta_B" boundaryCondition="false" compartment="Cell"/>
<species id="C" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="C" metaid="meta_C" boundaryCondition="false" compartment="Cell"/>
<species id="D" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="D" metaid="meta_D" boundaryCondition="false" compartment="Cell"/>
<species id="E" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="E" metaid="meta_E" boundaryCondition="false" compartment="Cell"/>
<species id="F" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="F" metaid="meta_F" boundaryCondition="false" compartment="Cell"/>
<species id="G" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="G" metaid="meta_G" boundaryCondition="false" compartment="Cell"/>
<species id="H" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="H" metaid="meta_H" boundaryCondition="false" compartment="Cell"/>
<species id="I" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="I" metaid="meta_I" boundaryCondition="false" compartment="Cell"/>
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<species id="P" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="P" metaid="meta_P" boundaryCondition="false" compartment="Cell"/>
<species id="Q" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="Q" metaid="meta_Q" boundaryCondition="false" compartment="Cell"/>
<species id="R" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="R" metaid="meta_R" boundaryCondition="false" compartment="Cell"/>
<species id="S" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="S" metaid="meta_S" boundaryCondition="false" compartment="Cell"/>
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<species id="U" fbc:charge="1" initialConcentration="0" fbc:chemicalFormula="C2H6O" constant="false" hasOnlySubstanceUnits="false" name="U" metaid="meta_U" boundaryCondition="true" compartment="Cell"/>
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<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
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<listOfProducts>
<speciesReference constant="false" species="M" stoichiometry="1"/>
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<reaction id="R14" name="R14" metaid="meta_R14" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
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<speciesReference constant="false" species="K" stoichiometry="1"/>
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<listOfProducts>
<speciesReference constant="false" species="L" stoichiometry="1"/>
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</reaction>
<reaction id="R15" name="R15" metaid="meta_R15" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
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<speciesReference constant="false" species="L" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="Q" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R12" name="R12" metaid="meta_R12" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
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<listOfProducts>
<speciesReference constant="false" species="J" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R07" name="R07" metaid="meta_R07" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
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<speciesReference constant="false" species="E" stoichiometry="1"/>
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<listOfProducts>
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</listOfProducts>
</reaction>
<reaction id="R13" name="R13" metaid="meta_R13" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
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<listOfProducts>
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<reaction id="R01" name="R01" metaid="meta_R01" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
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<listOfReactants>
<speciesReference constant="false" species="X" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="A" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R17" name="R17" metaid="meta_R17" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
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<speciesReference constant="false" species="M" stoichiometry="1"/>
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<listOfProducts>
<speciesReference constant="false" species="N" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R03" name="R03" metaid="meta_R03" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C1</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C1"/>
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<listOfReactants>
<speciesReference constant="false" species="A" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="C" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R02" name="R02" metaid="meta_R02" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C1</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C1"/>
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<listOfReactants>
<speciesReference constant="false" species="A" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="B" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R05" name="R05" metaid="meta_R05" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
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<listOfReactants>
<speciesReference constant="false" species="B" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="D" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R04" name="R04" metaid="meta_R04" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C1</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C1"/>
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<listOfReactants>
<speciesReference constant="false" species="C" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="B" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R10" name="R10" metaid="meta_R10" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
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</annotation>
<listOfReactants>
<speciesReference constant="false" species="G" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="H" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R06" name="R06" metaid="meta_R06" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
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<listOfReactants>
<speciesReference constant="false" species="D" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="E" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R09" name="R09" metaid="meta_R09" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
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<listOfReactants>
<speciesReference constant="false" species="D" stoichiometry="1"/>
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<listOfProducts>
<speciesReference constant="false" species="G" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R08" name="R08" metaid="meta_R08" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
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</annotation>
<listOfReactants>
<speciesReference constant="false" species="F" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="I" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R11" name="R11" metaid="meta_R11" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
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</annotation>
<listOfReactants>
<speciesReference constant="false" species="H" stoichiometry="1"/>
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<listOfProducts>
<speciesReference constant="false" species="I" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R18" name="R18" metaid="meta_R18" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
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<listOfReactants>
<speciesReference constant="false" species="N" stoichiometry="1"/>
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<listOfProducts>
<speciesReference constant="false" species="Q" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R19" name="R19" metaid="meta_R19" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="K" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="O" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R26" name="R26" metaid="meta_R26" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="S" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="Y" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R25" name="R25" metaid="meta_R25" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="A" stoichiometry="1"/>
<speciesReference constant="false" species="T" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="S" stoichiometry="0.5"/>
<speciesReference constant="false" species="U" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R23" name="R23" metaid="meta_R23" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C4</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C4"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="R" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="S" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R22" name="R22" metaid="meta_R22" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="Q" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="R" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R21" name="R21" metaid="meta_R21" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="P" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="L" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R20" name="R20" metaid="meta_R20" reversible="true" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="O" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="P" stoichiometry="1"/>
</listOfProducts>
</reaction>
<reaction id="R24" name="R24" metaid="meta_R24" reversible="false" fast="false">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C4</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C4"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference constant="false" species="R" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="false" species="S" stoichiometry="1"/>
</listOfProducts>
</reaction>
</listOfReactions>
</model>
</sbml>

View file

@ -0,0 +1,19 @@
#Graph Data
#Mon Jun 17 15:21:31 MDT 2013
visibleLegend=true
x.axis=time
auto.resize=true
y.max=
plot.domain.grid.line.paint=-4144960
x.max=
plot.background.paint=-1
y.axis=amount
chart.background.paint=-1118482
x.scale=
LogY=false
LogX=false
title=MODEL_01196 simulation results
plot.range.grid.line.paint=-4144960
y.min=
y.scale=
x.min=

View file

@ -0,0 +1,11 @@
#Probability Data
#Mon Jun 17 15:21:31 MDT 2013
visibleLegend=true
x.axis=
plot.background.paint=-1
y.axis=Percent
chart.background.paint=-1118482
title=MODEL_01196 simulation results
gradient=false
plot.range.grid.line.paint=-4144960
shadow=false

View file

@ -0,0 +1,27 @@
#MODEL_01196 Properties
#Mon Jun 17 15:21:31 MDT 2013
reb2sac.operator.max.concentration.threshold=15
reb2sac.qssa.condition.1=0.1
monte.carlo.simulation.time.step=inf
monte.carlo.simulation.print.interval=1.0
monte.carlo.simulation.runs=1
reb2sac.simulation.method=FBA
ode.simulation.time.limit=100.0
simulation.run.termination.decider=constraint
reb2sac.generate.statistics=false
monte.carlo.simulation.random.seed=314159
ode.simulation.time.step=inf
ode.simulation.out.dir=.
monte.carlo.simulation.time.limit=100.0
simulation.printer.tracking.quantity=amount
simulation.printer=tsd.printer
monte.carlo.simulation.min.time.step=0.0
ode.simulation.absolute.error=1.0E-9
ode.simulation.print.interval=1.0
ode.simulation.min.time.step=0.0
reb2sac.abstraction.method=none
reb2sac.rapid.equilibrium.condition.2=0.1
reb2sac.diffusion.stoichiometry.amplification.value=1.0
reb2sac.rapid.equilibrium.condition.1=0.1
monte.carlo.simulation.out.dir=.
selected.simulator=rkf45

View file

@ -0,0 +1,2 @@
MODEL_01196.xml

View file

@ -0,0 +1,638 @@
<?xml version="1.0" encoding="UTF-8"?>
<sbml xmlns="http://www.sbml.org/sbml/level3/version1/core" xmlns:fbc="http://www.sbml.org/sbml/level3/version1/fbc/version1" xmlns:html="http://www.w3.org/1999/xhtml" level="3" version="1" fbc:required="false">
<model metaid="meta_MODEL_01196" id="MODEL_01196" name="Created by iBioSim flatten routine" substanceUnits="mole" volumeUnits="litre">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>
<html:span style="font-family: Courier New,Courier,monospace;">Infeasible solution, should return a nan</html:span>
</html:p>
</body>
</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Description rdf:about="#meta_MODEL_01196">
<dc:creator>
<rdf:Bag>
<rdf:li rdf:parseType="Resource">
<vCard:N rdf:parseType="Resource">
<vCard:Family>Olivier</vCard:Family>
<vCard:Given>Brett</vCard:Given>
</vCard:N>
<vCard:EMAIL>bgoli@users.sourceforge.net</vCard:EMAIL>
<vCard:ORG rdf:parseType="Resource">
<vCard:Orgname>VU university Amsterdam</vCard:Orgname>
</vCard:ORG>
</rdf:li>
</rdf:Bag>
</dc:creator>
<dcterms:created rdf:parseType="Resource">
<dcterms:W3CDTF>2012-12-21T11:05:22Z</dcterms:W3CDTF>
</dcterms:created>
<dcterms:modified rdf:parseType="Resource">
<dcterms:W3CDTF>2012-12-21T10:05:22Z</dcterms:W3CDTF>
</dcterms:modified>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfUnitDefinitions>
<unitDefinition id="substance" name="substance">
<listOfUnits>
<unit kind="mole" exponent="1" scale="0" multiplier="1"/>
</listOfUnits>
</unitDefinition>
<unitDefinition id="area" name="area">
<listOfUnits>
<unit kind="metre" exponent="2" scale="0" multiplier="1"/>
</listOfUnits>
</unitDefinition>
<unitDefinition id="volume" name="volume">
<listOfUnits>
<unit kind="litre" exponent="1" scale="0" multiplier="1"/>
</listOfUnits>
</unitDefinition>
<unitDefinition id="length" name="length">
<listOfUnits>
<unit kind="metre" exponent="1" scale="0" multiplier="1"/>
</listOfUnits>
</unitDefinition>
<unitDefinition id="time" name="time">
<listOfUnits>
<unit kind="second" exponent="1" scale="0" multiplier="1"/>
</listOfUnits>
</unitDefinition>
<unitDefinition id="mmol_per_gDW_per_hr" name="mmol_per_gDW_per_hr">
<listOfUnits>
<unit kind="mole" exponent="1" scale="-3" multiplier="1"/>
<unit kind="gram" exponent="-1" scale="0" multiplier="1"/>
<unit kind="second" exponent="-1" scale="0" multiplier="0.00027777"/>
</listOfUnits>
</unitDefinition>
<unitDefinition id="u_1_second_n1">
<listOfUnits>
<unit kind="second" exponent="-1" scale="0" multiplier="1"/>
</listOfUnits>
</unitDefinition>
</listOfUnitDefinitions>
<listOfCompartments>
<compartment id="Cell" name="Cell" size="1" constant="false"/>
</listOfCompartments>
<listOfSpecies>
<species metaid="meta_A" id="A" name="A" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_B" id="B" name="B" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_C" id="C" name="C" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_D" id="D" name="D" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_E" id="E" name="E" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_F" id="F" name="F" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_G" id="G" name="G" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_H" id="H" name="H" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_I" id="I" name="I" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_J" id="J" name="J" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_K" id="K" name="K" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_L" id="L" name="L" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_M" id="M" name="M" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_N" id="N" name="N" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_O" id="O" name="O" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_P" id="P" name="P" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_Q" id="Q" name="Q" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_R" id="R" name="R" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_S" id="S" name="S" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_T" id="T" name="T" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="true" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_U" id="U" name="U" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="true" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_X" id="X" name="X" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="true" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
<species metaid="meta_Y" id="Y" name="Y" compartment="Cell" initialConcentration="0" hasOnlySubstanceUnits="false" boundaryCondition="true" constant="false" fbc:charge="1" fbc:chemicalFormula="C2H6O"/>
</listOfSpecies>
<listOfReactions>
<reaction metaid="meta_R16" id="R16" name="R16" reversible="false" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="J" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="M" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R14" id="R14" name="R14" reversible="true" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="K" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="L" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R15" id="R15" name="R15" reversible="false" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="L" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Q" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R12" id="R12" name="R12" reversible="false" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="I" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="J" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R07" id="R07" name="R07" reversible="false" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="E" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="F" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R13" id="R13" name="R13" reversible="false" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="J" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="K" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R01" id="R01" name="R01" reversible="false" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="X" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="A" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R17" id="R17" name="R17" reversible="false" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="M" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="N" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R03" id="R03" name="R03" reversible="true" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C1</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C1"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="A" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="C" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R02" id="R02" name="R02" reversible="true" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C1</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C1"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="A" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="B" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R05" id="R05" name="R05" reversible="false" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="B" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="D" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R04" id="R04" name="R04" reversible="true" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C1</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C1"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="C" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="B" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R10" id="R10" name="R10" reversible="false" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="G" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="H" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R06" id="R06" name="R06" reversible="false" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="D" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="E" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R09" id="R09" name="R09" reversible="false" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="D" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="G" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R08" id="R08" name="R08" reversible="false" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="F" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="I" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R11" id="R11" name="R11" reversible="false" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C2</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C2"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="H" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="I" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R18" id="R18" name="R18" reversible="false" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="N" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Q" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R19" id="R19" name="R19" reversible="true" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="K" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="O" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R26" id="R26" name="R26" reversible="false" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="S" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Y" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R25" id="R25" name="R25" reversible="false" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="A" stoichiometry="1" constant="false"/>
<speciesReference species="T" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S" stoichiometry="0.5" constant="false"/>
<speciesReference species="U" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R23" id="R23" name="R23" reversible="true" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C4</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C4"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="R" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R22" id="R22" name="R22" reversible="false" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: L</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="L"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="Q" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="R" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R21" id="R21" name="R21" reversible="true" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="P" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="L" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R20" id="R20" name="R20" reversible="true" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C3</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C3"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="O" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="P" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
<reaction metaid="meta_R24" id="R24" name="R24" reversible="false" fast="false">
<notes>
<body xmlns:html="http://www.w3.org/1999/xhtml">
<html:p>subsystem: C4</html:p>
</body>
</notes>
<annotation>
<listOfKeyValueData xmlns="http://pysces.sourceforge.net/KeyValueData">
<data id="subsystem" type="string" value="C4"/>
</listOfKeyValueData>
</annotation>
<listOfReactants>
<speciesReference species="R" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S" stoichiometry="1" constant="false"/>
</listOfProducts>
</reaction>
</listOfReactions>
<fbc:listOfFluxBounds>
<fbc:fluxBound fbc:id="c0" fbc:reaction="R16" fbc:operation="greaterEqual" fbc:value="0"/>
<fbc:fluxBound fbc:id="c1" fbc:reaction="R16" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c2" fbc:reaction="R03" fbc:operation="greaterEqual" fbc:value="-1000"/>
<fbc:fluxBound fbc:id="c3" fbc:reaction="R03" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c4" fbc:reaction="R02" fbc:operation="greaterEqual" fbc:value="-1000"/>
<fbc:fluxBound fbc:id="c5" fbc:reaction="R02" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c6" fbc:reaction="R05" fbc:operation="greaterEqual" fbc:value="0"/>
<fbc:fluxBound fbc:id="c7" fbc:reaction="R05" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c8" fbc:reaction="R07" fbc:operation="greaterEqual" fbc:value="2"/>
<fbc:fluxBound fbc:id="c9" fbc:reaction="R07" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c10" fbc:reaction="R04" fbc:operation="greaterEqual" fbc:value="-1000"/>
<fbc:fluxBound fbc:id="c11" fbc:reaction="R04" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c12" fbc:reaction="R01" fbc:operation="greaterEqual" fbc:value="0"/>
<fbc:fluxBound fbc:id="c13" fbc:reaction="R01" fbc:operation="lessEqual" fbc:value="1"/>
<fbc:fluxBound fbc:id="c14" fbc:reaction="R17" fbc:operation="greaterEqual" fbc:value="0"/>
<fbc:fluxBound fbc:id="c15" fbc:reaction="R17" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c16" fbc:reaction="R14" fbc:operation="greaterEqual" fbc:value="-1000"/>
<fbc:fluxBound fbc:id="c17" fbc:reaction="R14" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c18" fbc:reaction="R15" fbc:operation="greaterEqual" fbc:value="0"/>
<fbc:fluxBound fbc:id="c19" fbc:reaction="R15" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c20" fbc:reaction="R12" fbc:operation="greaterEqual" fbc:value="0"/>
<fbc:fluxBound fbc:id="c21" fbc:reaction="R12" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c22" fbc:reaction="R13" fbc:operation="greaterEqual" fbc:value="0"/>
<fbc:fluxBound fbc:id="c23" fbc:reaction="R13" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c24" fbc:reaction="R10" fbc:operation="greaterEqual" fbc:value="0"/>
<fbc:fluxBound fbc:id="c25" fbc:reaction="R10" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c26" fbc:reaction="R11" fbc:operation="greaterEqual" fbc:value="0"/>
<fbc:fluxBound fbc:id="c27" fbc:reaction="R11" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c28" fbc:reaction="R09" fbc:operation="greaterEqual" fbc:value="0"/>
<fbc:fluxBound fbc:id="c29" fbc:reaction="R09" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c30" fbc:reaction="R08" fbc:operation="greaterEqual" fbc:value="0"/>
<fbc:fluxBound fbc:id="c31" fbc:reaction="R08" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c32" fbc:reaction="R06" fbc:operation="greaterEqual" fbc:value="0"/>
<fbc:fluxBound fbc:id="c33" fbc:reaction="R06" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c34" fbc:reaction="R18" fbc:operation="greaterEqual" fbc:value="0"/>
<fbc:fluxBound fbc:id="c35" fbc:reaction="R18" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c36" fbc:reaction="R19" fbc:operation="greaterEqual" fbc:value="-1000"/>
<fbc:fluxBound fbc:id="c37" fbc:reaction="R19" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c38" fbc:reaction="R26" fbc:operation="greaterEqual" fbc:value="0"/>
<fbc:fluxBound fbc:id="c39" fbc:reaction="R26" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c40" fbc:reaction="R25" fbc:operation="greaterEqual" fbc:value="0"/>
<fbc:fluxBound fbc:id="c41" fbc:reaction="R25" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c42" fbc:reaction="R24" fbc:operation="greaterEqual" fbc:value="0"/>
<fbc:fluxBound fbc:id="c43" fbc:reaction="R24" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c44" fbc:reaction="R23" fbc:operation="greaterEqual" fbc:value="-1000"/>
<fbc:fluxBound fbc:id="c45" fbc:reaction="R23" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c46" fbc:reaction="R22" fbc:operation="greaterEqual" fbc:value="0"/>
<fbc:fluxBound fbc:id="c47" fbc:reaction="R22" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c48" fbc:reaction="R21" fbc:operation="greaterEqual" fbc:value="-1000"/>
<fbc:fluxBound fbc:id="c49" fbc:reaction="R21" fbc:operation="lessEqual" fbc:value="1000"/>
<fbc:fluxBound fbc:id="c50" fbc:reaction="R20" fbc:operation="greaterEqual" fbc:value="-1000"/>
<fbc:fluxBound fbc:id="c51" fbc:reaction="R20" fbc:operation="lessEqual" fbc:value="1000"/>
</fbc:listOfFluxBounds>
<fbc:listOfObjectives fbc:activeObjective="OBJF">
<fbc:objective fbc:id="OBJF" fbc:type="maximize">
<fbc:listOfFluxObjectives>
<fbc:fluxObjective fbc:reaction="R26" fbc:coefficient="1"/>
</fbc:listOfFluxObjectives>
</fbc:objective>
</fbc:listOfObjectives>
</model>
</sbml>

View file

@ -0,0 +1,3 @@
Total Simulation Time: 0.02813 seconds for MODEL_01196

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@ -0,0 +1 @@
[]

View file

@ -0,0 +1,466 @@
<?xml version="1.0" encoding="UTF-8"?>
<sbml xmlns="http://www.sbml.org/sbml/level3/version1/core" xmlns:layout="http://www.sbml.org/sbml/level3/version1/layout/version1" xmlns:comp="http://www.sbml.org/sbml/level3/version1/comp/version1" level="3" version="1" layout:required="false" comp:required="true">
<model metaid="iBioSim1" id="Population">
<listOfFunctionDefinitions>
<functionDefinition id="get2DArrayElement" name="get2DArrayElement">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<lambda>
<bvar>
<ci> a </ci>
</bvar>
<bvar>
<ci> b </ci>
</bvar>
<bvar>
<ci> c </ci>
</bvar>
<ci> a </ci>
</lambda>
</math>
</functionDefinition>
</listOfFunctionDefinitions>
<listOfUnitDefinitions>
<unitDefinition id="u_1_second_n1">
<listOfUnits>
<unit kind="second" exponent="-1" scale="0" multiplier="1"/>
</listOfUnits>
</unitDefinition>
</listOfUnitDefinitions>
<listOfCompartments>
<compartment id="Grid" spatialDimensions="3" size="1" constant="true">
<annotation>
<ibiosim:ibiosim xmlns:ibiosim="http://www.fakeuri.com" ibiosim:grid="(1,2)"/>
</annotation>
</compartment>
</listOfCompartments>
<listOfSpecies>
<species metaid="iBioSim26" id="CII" compartment="Grid" initialAmount="0" hasOnlySubstanceUnits="true" boundaryCondition="false" constant="false">
<annotation>
<ibiosim:ibiosim xmlns:ibiosim="http://www.fakeuri.com" ibiosim:grid="(1,2)"/>
</annotation>
</species>
</listOfSpecies>
<listOfParameters>
<parameter metaid="iBioSim2" id="kr_f" name="Forward repression binding rate" value="0.5" constant="true"/>
<parameter metaid="iBioSim3" id="kr_r" name="Reverse repression binding rate" value="1" constant="true"/>
<parameter metaid="iBioSim4" id="ka_f" name="Forward activation binding rate" value="0.0033" constant="true"/>
<parameter metaid="iBioSim5" id="ka_r" name="Reverse activation binding rate" value="1" constant="true"/>
<parameter metaid="iBioSim6" id="ko_f" name="Forward RNAP binding rate" value="0.033" constant="true"/>
<parameter metaid="iBioSim7" id="ko_r" name="Reverse RNAP binding rate" value="1" constant="true"/>
<parameter metaid="iBioSim8" id="kao_f" name="Forward activated RNAP binding rate" value="1" constant="true"/>
<parameter metaid="iBioSim9" id="kao_r" name="Reverse activated RNAP binding rate" value="1" constant="true"/>
<parameter metaid="iBioSim10" id="kc_f" name="Forward complex formation rate" value="0.05" constant="true"/>
<parameter metaid="iBioSim11" id="kc_r" name="Reverse complex formation rate" value="1" constant="true"/>
<parameter metaid="iBioSim12" id="kmdiff_f" name="Forward membrane diffusion rate" value="1" constant="true"/>
<parameter metaid="iBioSim13" id="kmdiff_r" name="Reverse membrane diffusion rate" value="0.01" constant="true"/>
<parameter metaid="iBioSim14" id="kd" name="Degradation rate" value="0.0075" constant="true"/>
<parameter metaid="iBioSim15" id="kecd" name="Extracellular degradation rate" value="0.005" constant="true"/>
<parameter metaid="iBioSim16" id="nc" name="Stoichiometry of binding" value="2" constant="true"/>
<parameter metaid="iBioSim17" id="nr" name="Initial RNAP count" value="30" constant="true"/>
<parameter metaid="iBioSim18" id="ko" name="Open complex production rate" value="0.05" constant="true"/>
<parameter metaid="iBioSim19" id="kb" name="Basal production rate" value="0.0001" constant="true"/>
<parameter metaid="iBioSim20" id="ng" name="Initial promoter count" value="2" constant="true"/>
<parameter metaid="iBioSim21" id="np" name="Stoichiometry of production" value="10" constant="true"/>
<parameter metaid="iBioSim22" id="ka" name="Activated production rate" value="0.25" constant="true"/>
<parameter metaid="iBioSim23" id="kecdiff" name="Extracellular diffusion rate" value="1" constant="true"/>
<parameter metaid="iBioSim24" id="lambda__locations" value="0" constant="false">
<annotation>
<array:array xmlns:array="http://www.fakeuri.com" array:C1="(0,0)"/>
</annotation>
</parameter>
<parameter id="Divide__locations" value="0" constant="false">
<annotation>
<array:array xmlns:array="http://www.fakeuri.com" array:C2="(0,1)"/>
</annotation>
</parameter>
</listOfParameters>
<listOfReactions>
<reaction metaid="Degradation_CII" sboTerm="SBO:0000179" id="Degradation_CII" reversible="false" fast="false" compartment="Grid">
<annotation>
<ibiosim:ibiosim xmlns:ibiosim="http://www.fakeuri.com" ibiosim:grid="(1,2)"/>
</annotation>
<listOfReactants>
<speciesReference species="CII" stoichiometry="1" constant="false"/>
</listOfReactants>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> kecd </ci>
<apply>
<ci> get2DArrayElement </ci>
<ci> CII </ci>
<ci> i </ci>
<ci> j </ci>
</apply>
</apply>
</math>
<listOfLocalParameters>
<localParameter id="i">
<annotation>
<array:array xmlns:array="http://www.fakeuri.com" array:size="0"/>
</annotation>
</localParameter>
<localParameter id="j">
<annotation>
<array:array xmlns:array="http://www.fakeuri.com" array:size="1"/>
</annotation>
</localParameter>
<localParameter id="kecd" value="0.005" units="u_1_second_n1"/>
</listOfLocalParameters>
</kineticLaw>
</reaction>
<reaction metaid="Diffusion_CII_Above" id="Diffusion_CII_Above" reversible="true" fast="false" compartment="Grid">
<annotation>
<ibiosim:ibiosim xmlns:ibiosim="http://www.fakeuri.com" ibiosim:grid="(1,2)"/>
</annotation>
<listOfReactants>
<speciesReference species="CII" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="CII" stoichiometry="1" constant="false"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<minus/>
<apply>
<times/>
<ci> kecdiff </ci>
<apply>
<ci> get2DArrayElement </ci>
<ci> CII </ci>
<ci> i </ci>
<ci> j </ci>
</apply>
</apply>
<apply>
<times/>
<ci> kecdiff </ci>
<apply>
<ci> get2DArrayElement </ci>
<ci> CII </ci>
<apply>
<minus/>
<ci> i </ci>
<cn type="integer"> 1 </cn>
</apply>
<apply>
<plus/>
<ci> j </ci>
<cn type="integer"> 0 </cn>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfLocalParameters>
<localParameter id="i">
<annotation>
<array:array xmlns:array="http://www.fakeuri.com" array:size="0"/>
</annotation>
</localParameter>
<localParameter id="j">
<annotation>
<array:array xmlns:array="http://www.fakeuri.com" array:size="1"/>
</annotation>
</localParameter>
<localParameter id="kecdiff" value="1" units="u_1_second_n1"/>
</listOfLocalParameters>
</kineticLaw>
</reaction>
<reaction metaid="Diffusion_CII_Below" id="Diffusion_CII_Below" reversible="true" fast="false" compartment="Grid">
<annotation>
<ibiosim:ibiosim xmlns:ibiosim="http://www.fakeuri.com" ibiosim:grid="(1,2)"/>
</annotation>
<listOfReactants>
<speciesReference species="CII" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="CII" stoichiometry="1" constant="false"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<minus/>
<apply>
<times/>
<ci> kecdiff </ci>
<apply>
<ci> get2DArrayElement </ci>
<ci> CII </ci>
<ci> i </ci>
<ci> j </ci>
</apply>
</apply>
<apply>
<times/>
<ci> kecdiff </ci>
<apply>
<ci> get2DArrayElement </ci>
<ci> CII </ci>
<apply>
<plus/>
<ci> i </ci>
<cn type="integer"> 1 </cn>
</apply>
<apply>
<plus/>
<ci> j </ci>
<cn type="integer"> 0 </cn>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfLocalParameters>
<localParameter id="i">
<annotation>
<array:array xmlns:array="http://www.fakeuri.com" array:size="0"/>
</annotation>
</localParameter>
<localParameter id="j">
<annotation>
<array:array xmlns:array="http://www.fakeuri.com" array:size="1"/>
</annotation>
</localParameter>
<localParameter id="kecdiff" value="1" units="u_1_second_n1"/>
</listOfLocalParameters>
</kineticLaw>
</reaction>
<reaction metaid="Diffusion_CII_Left" id="Diffusion_CII_Left" reversible="true" fast="false" compartment="Grid">
<annotation>
<ibiosim:ibiosim xmlns:ibiosim="http://www.fakeuri.com" ibiosim:grid="(1,2)"/>
</annotation>
<listOfReactants>
<speciesReference species="CII" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="CII" stoichiometry="1" constant="false"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<minus/>
<apply>
<times/>
<ci> kecdiff </ci>
<apply>
<ci> get2DArrayElement </ci>
<ci> CII </ci>
<ci> i </ci>
<ci> j </ci>
</apply>
</apply>
<apply>
<times/>
<ci> kecdiff </ci>
<apply>
<ci> get2DArrayElement </ci>
<ci> CII </ci>
<apply>
<plus/>
<ci> i </ci>
<cn type="integer"> 0 </cn>
</apply>
<apply>
<minus/>
<ci> j </ci>
<cn type="integer"> 1 </cn>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfLocalParameters>
<localParameter id="i">
<annotation>
<array:array xmlns:array="http://www.fakeuri.com" array:size="0"/>
</annotation>
</localParameter>
<localParameter id="j">
<annotation>
<array:array xmlns:array="http://www.fakeuri.com" array:size="1"/>
</annotation>
</localParameter>
<localParameter id="kecdiff" value="1" units="u_1_second_n1"/>
</listOfLocalParameters>
</kineticLaw>
</reaction>
<reaction metaid="Diffusion_CII_Right" id="Diffusion_CII_Right" reversible="true" fast="false" compartment="Grid">
<annotation>
<ibiosim:ibiosim xmlns:ibiosim="http://www.fakeuri.com" ibiosim:grid="(1,2)"/>
</annotation>
<listOfReactants>
<speciesReference species="CII" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="CII" stoichiometry="1" constant="false"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<minus/>
<apply>
<times/>
<ci> kecdiff </ci>
<apply>
<ci> get2DArrayElement </ci>
<ci> CII </ci>
<ci> i </ci>
<ci> j </ci>
</apply>
</apply>
<apply>
<times/>
<ci> kecdiff </ci>
<apply>
<ci> get2DArrayElement </ci>
<ci> CII </ci>
<apply>
<plus/>
<ci> i </ci>
<cn type="integer"> 0 </cn>
</apply>
<apply>
<plus/>
<ci> j </ci>
<cn type="integer"> 1 </cn>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfLocalParameters>
<localParameter id="i">
<annotation>
<array:array xmlns:array="http://www.fakeuri.com" array:size="0"/>
</annotation>
</localParameter>
<localParameter id="j">
<annotation>
<array:array xmlns:array="http://www.fakeuri.com" array:size="1"/>
</annotation>
</localParameter>
<localParameter id="kecdiff" value="1" units="u_1_second_n1"/>
</listOfLocalParameters>
</kineticLaw>
</reaction>
<reaction metaid="MembraneDiffusion_CII" id="MembraneDiffusion_CII" reversible="true" fast="false" compartment="Grid">
<annotation>
<ibiosim:ibiosim xmlns:ibiosim="http://www.fakeuri.com" ibiosim:type="grid"/>
</annotation>
<listOfReactants>
<speciesReference species="CII" stoichiometry="1" constant="false"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="CII" stoichiometry="1" constant="false"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<minus/>
<apply>
<times/>
<apply>
<ci> get2DArrayElement </ci>
<ci> kmdiff_f </ci>
<ci> i </ci>
<ci> j </ci>
</apply>
<apply>
<ci> get2DArrayElement </ci>
<ci> CII </ci>
<ci> i </ci>
<ci> j </ci>
</apply>
</apply>
<apply>
<times/>
<apply>
<ci> get2DArrayElement </ci>
<ci> kmdiff_r </ci>
<ci> i </ci>
<ci> j </ci>
</apply>
<apply>
<ci> get2DArrayElement </ci>
<ci> CII </ci>
<ci> i </ci>
<ci> j </ci>
</apply>
</apply>
</apply>
</math>
<listOfLocalParameters>
<localParameter id="i">
<annotation>
<array:array xmlns:array="http://www.fakeuri.com" array:size="0"/>
</annotation>
</localParameter>
<localParameter id="j">
<annotation>
<array:array xmlns:array="http://www.fakeuri.com" array:size="1"/>
</annotation>
</localParameter>
</listOfLocalParameters>
</kineticLaw>
</reaction>
</listOfReactions>
<layout:listOfLayouts xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:layout="http://www.sbml.org/sbml/level3/version1/layout/version1">
<layout:layout layout:id="iBioSim">
<layout:dimensions layout:width="0" layout:height="0"/>
<layout:listOfTextGlyphs>
<layout:textGlyph layout:id="TextGlyph__C1" layout:text="C1" layout:graphicalObject="Glyph__C1">
<layout:boundingBox>
<layout:position layout:x="30" layout:y="30"/>
<layout:dimensions layout:width="80" layout:height="40"/>
</layout:boundingBox>
</layout:textGlyph>
<layout:textGlyph layout:id="TextGlyph__C2" layout:text="C2" layout:graphicalObject="Glyph__C2">
<layout:boundingBox>
<layout:position layout:x="140" layout:y="30"/>
<layout:dimensions layout:width="80" layout:height="40"/>
</layout:boundingBox>
</layout:textGlyph>
</layout:listOfTextGlyphs>
<layout:listOfAdditionalGraphicalObjects>
<layout:generalGlyph layout:id="Glyph__C1" layout:reference="C1">
<layout:boundingBox>
<layout:position layout:x="30" layout:y="30"/>
<layout:dimensions layout:width="80" layout:height="40"/>
</layout:boundingBox>
</layout:generalGlyph>
<layout:generalGlyph layout:id="Glyph__C2" layout:reference="C2">
<layout:boundingBox>
<layout:position layout:x="140" layout:y="30"/>
<layout:dimensions layout:width="80" layout:height="40"/>
</layout:boundingBox>
</layout:generalGlyph>
</layout:listOfAdditionalGraphicalObjects>
</layout:layout>
</layout:listOfLayouts>
<comp:listOfSubmodels>
<comp:submodel metaid="iBioSim25" comp:id="GRID__lambda" comp:modelRef="lambda">
<annotation>
<array:array xmlns:array="http://www.fakeuri.com" array:size="1"/>
</annotation>
<comp:listOfDeletions>
<comp:deletion comp:portRef="rule__Total"/>
<comp:deletion comp:portRef="constraint__CI20"/>
<comp:deletion comp:portRef="constraint__CII50"/>
<comp:deletion comp:portRef="event__CellDivision"/>
</comp:listOfDeletions>
</comp:submodel>
<comp:submodel comp:id="GRID__Divide" comp:modelRef="Divide">
<annotation>
<array:array xmlns:array="http://www.fakeuri.com" array:size="1"/>
</annotation>
</comp:submodel>
</comp:listOfSubmodels>
</model>
<comp:listOfExternalModelDefinitions>
<comp:externalModelDefinition comp:id="lambda" comp:source="file:lambda.xml" comp:md5="9fb1f105f55254ab934bf32ed25a0708"/>
<comp:externalModelDefinition comp:id="Divide" comp:source="file:Divide.xml" comp:md5="0a417cb64224a4ab9c9b82acab9082d4"/>
</comp:listOfExternalModelDefinitions>
</sbml>

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#Graph Data
#Mon Jun 10 14:26:23 MDT 2013
species.filled.2=true
species.filled.1=true
species.filled.0=true
chart.background.paint=-1118482
species.connected.3=true
plot.background.paint=-1
species.connected.2=true
species.connected.1=true
species.connected.0=true
species.xnumber.3=0
species.xnumber.2=0
y.max=62.7
species.id.3=C11__CII (1)
species.xnumber.1=0
species.id.2=C11__CII (1)
species.xnumber.0=0
auto.resize=true
species.id.1=C10__CII (1)
species.number.3=17
species.id.0=C10__C1__S0 (1)
species.number.2=17
species.visible.3=true
species.number.1=5
species.visible.2=true
y.axis=amount
species.number.0=0
species.visible.1=true
species.visible.0=true
species.paint.3=Green
species.paint.2=Yellow
species.directory.3=
species.paint.1=Red
species.directory.2=
species.paint.0=Blue
species.directory.1=
species.directory.0=
x.max=500.0
title=Population simulation results
y.scale=5.0
x.scale=25.0
species.shape.3=Triangle
species.name.3=C11__CII(\u03C7)
y.min=0.0
species.shape.2=Diamond
species.name.2=C11__CII(1)
species.shape.1=Square
species.name.1=C10__CII (1)
species.name.0=C10__C1__S0 (1)
species.shape.0=Circle
x.axis=time
LogY=false
LogX=false
plot.range.grid.line.paint=-4144960
plot.domain.grid.line.paint=-4144960
species.run.number.3=Average
species.run.number.2=run-1
species.run.number.1=run-1
species.run.number.0=run-1
visibleLegend=true
species.filled.3=true
x.min=0.0

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#Probability Data
#Sun Jun 09 18:21:36 MDT 2013
visibleLegend=true
x.axis=
plot.background.paint=-1
y.axis=Percent
chart.background.paint=-1118482
title=Population simulation results
gradient=false
plot.range.grid.line.paint=-4144960
shadow=false

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#Population Properties
#Sun Jun 23 12:47:27 MDT 2013
reb2sac.operator.max.concentration.threshold=15
reb2sac.qssa.condition.1=0.1
monte.carlo.simulation.time.step=inf
monte.carlo.simulation.print.interval=10.0
monte.carlo.simulation.runs=2
reb2sac.simulation.method=Browser
ode.simulation.time.limit=500.0
simulation.run.termination.decider=constraint
reb2sac.generate.statistics=false
monte.carlo.simulation.random.seed=314159
ode.simulation.time.step=inf
ode.simulation.out.dir=.
monte.carlo.simulation.time.limit=500.0
simulation.printer.tracking.quantity=amount
simulation.printer=tsd.printer
monte.carlo.simulation.min.time.step=0.0
ode.simulation.absolute.error=1.0E-9
ode.simulation.print.interval=10.0
ode.simulation.min.time.step=0.0
reb2sac.abstraction.method=none
reb2sac.rapid.equilibrium.condition.2=0.1
reb2sac.diffusion.stoichiometry.amplification.value=1.0
reb2sac.rapid.equilibrium.condition.1=0.1
monte.carlo.simulation.out.dir=.
selected.simulator=rkf45

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Population.xml

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Executing:
reb2sac --target.encoding=xhtml --out=Population.xhtml /Users/myers/research/nobackup/workspace/BioSim/docs/Tutorial/Population/Population.xml
Total Simulation Time: 1.067807 second for Population
Executing:
open /Users/myers/research/nobackup/workspace/BioSim/docs/Tutorial/Population/Population.xhtml

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(("time"),(0.0),(10.0),(20.0),(30.0),(40.0),(50.0),(60.0),(70.0),(80.0),(90.0),(100.0),(110.0),(120.0),(130.0),(140.0),(150.0),(160.0),(170.0),(180.0),(190.0),(200.0),(210.0),(220.0),(230.0),(240.0),(250.0),(260.0),(270.0),(280.0),(290.0),(300.0),(310.0),(320.0),(330.0),(340.0),(350.0),(360.0),(370.0),(380.0),(390.0),(400.0),(410.0),(420.0),(430.0),(440.0),(450.0),(460.0),(470.0),(480.0),(490.0),(500.0))

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[]

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#total time-limit
2 2

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(("time"),(0.0),(10.0),(20.0),(30.0),(40.0),(50.0),(60.0),(70.0),(80.0),(90.0),(100.0),(110.0),(120.0),(130.0),(140.0),(150.0),(160.0),(170.0),(180.0),(190.0),(200.0),(210.0),(220.0),(230.0),(240.0),(250.0),(260.0),(270.0),(280.0),(290.0),(300.0),(310.0),(320.0),(330.0),(340.0),(350.0),(360.0),(370.0),(380.0),(390.0),(400.0),(410.0),(420.0),(430.0),(440.0),(450.0),(460.0),(470.0),(480.0),(490.0),(500.0))

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<?xml version='1.0' encoding='UTF-8' standalone='no'?>
<sbml xmlns="http://www.sbml.org/sbml/level3/version1/core" level="3" version="1">
<model id="SweepTest" metaid="iBioSim1">
<annotation>
</annotation>
<comp:listOfPorts xmlns:comp="http://www.sbml.org/sbml/level3/version1/comp/version1">
<comp:port comp:idRef="Cell" sboTerm="SBO:0000601" comp:id="compartment__Cell"/>
</comp:listOfPorts>
<layout:listOfLayouts xmlns:layout="http://www.sbml.org/sbml/level3/version1/layout/version1" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<layout:layout layout:id="iBioSim">
<layout:dimensions layout:width="0" layout:height="0" layout:depth="0"/>
<layout:listOfCompartmentGlyphs>
<layout:compartmentGlyph layout:id="Glyph__Cell" layout:compartment="Cell">
<layout:boundingBox>
<layout:position layout:x="0" layout:y="0"/>
<layout:dimensions layout:width="1070" layout:height="425"/>
</layout:boundingBox>
</layout:compartmentGlyph>
</layout:listOfCompartmentGlyphs>
<layout:listOfSpeciesGlyphs>
<layout:speciesGlyph layout:id="Glyph__S0" layout:species="S0">
<layout:boundingBox>
<layout:position layout:x="156" layout:y="87"/>
<layout:dimensions layout:width="100" layout:height="30"/>
</layout:boundingBox>
</layout:speciesGlyph>
</layout:listOfSpeciesGlyphs>
<layout:listOfReactionGlyphs>
<layout:reactionGlyph layout:id="Glyph__R0" layout:reaction="R0">
<layout:boundingBox>
<layout:position layout:x="213" layout:y="183"/>
<layout:dimensions layout:width="30" layout:height="30"/>
</layout:boundingBox>
<layout:listOfSpeciesReferenceGlyphs>
<layout:speciesReferenceGlyph layout:id="Glyph__R0__substrate__S0" layout:role="substrate" layout:speciesGlyph="Glyph__S0"/>
</layout:listOfSpeciesReferenceGlyphs>
</layout:reactionGlyph>
</layout:listOfReactionGlyphs>
<layout:listOfTextGlyphs>
<layout:textGlyph layout:graphicalObject="Glyph__Cell" layout:id="TextGlyph__Cell" layout:text="Cell">
<layout:boundingBox>
<layout:position layout:x="0" layout:y="0"/>
<layout:dimensions layout:width="1070" layout:height="425"/>
</layout:boundingBox>
</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__S0" layout:id="TextGlyph__S0" layout:text="S0">
<layout:boundingBox>
<layout:position layout:x="156" layout:y="87"/>
<layout:dimensions layout:width="100" layout:height="30"/>
</layout:boundingBox>
</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__R0" layout:id="TextGlyph__R0" layout:text="R0">
<layout:boundingBox>
<layout:position layout:x="213" layout:y="183"/>
<layout:dimensions layout:width="30" layout:height="30"/>
</layout:boundingBox>
</layout:textGlyph>
</layout:listOfTextGlyphs>
</layout:layout>
</layout:listOfLayouts>
<listOfCompartments>
<compartment id="Cell" constant="true" spatialDimensions="3" size="1">
<annotation>
</annotation>
</compartment>
</listOfCompartments>
<listOfSpecies>
<species id="S0" constant="false" initialAmount="100" hasOnlySubstanceUnits="true" metaid="iBioSim2" boundaryCondition="false" compartment="Cell">
<annotation>
</annotation>
</species>
</listOfSpecies>
<listOfReactions>
<reaction id="R0" metaid="iBioSim3" reversible="false" fast="false" compartment="Cell">
<listOfReactants>
<speciesReference constant="true" species="S0" stoichiometry="1"/>
</listOfReactants>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<ci> kf </ci>
</math>
<listOfLocalParameters>
<localParameter id="kf" value="0.1"/>
<localParameter id="kr" value="1"/>
</listOfLocalParameters>
</kineticLaw>
</reaction>
</listOfReactions>
</model>
</sbml>

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SweepTest.xml

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<?xml version="1.0" encoding="UTF-8"?>
<sbml xmlns="http://www.sbml.org/sbml/level3/version1/core" xmlns:layout="http://www.sbml.org/sbml/level3/version1/layout/version1" xmlns:comp="http://www.sbml.org/sbml/level3/version1/comp/version1" level="3" version="1" layout:required="false" comp:required="true">
<model metaid="iBioSim1" id="TestDivide">
<listOfFunctionDefinitions>
<functionDefinition id="get2DArrayElement" name="get2DArrayElement">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<lambda>
<bvar>
<ci> a </ci>
</bvar>
<bvar>
<ci> b </ci>
</bvar>
<bvar>
<ci> c </ci>
</bvar>
<ci> a </ci>
</lambda>
</math>
</functionDefinition>
</listOfFunctionDefinitions>
<listOfUnitDefinitions>
<unitDefinition id="u_1_second_n1">
<listOfUnits>
<unit kind="second" exponent="-1" scale="0" multiplier="1"/>
</listOfUnits>
</unitDefinition>
</listOfUnitDefinitions>
<listOfCompartments>
<compartment id="Grid" spatialDimensions="3" size="1" constant="true">
<annotation>
<ibiosim:ibiosim xmlns:ibiosim="http://www.fakeuri.com" ibiosim:grid="(1,1)"/>
</annotation>
</compartment>
</listOfCompartments>
<listOfParameters>
<parameter metaid="iBioSim2" id="kr_f" name="Forward repression binding rate" value="0.5" constant="true"/>
<parameter metaid="iBioSim3" id="kr_r" name="Reverse repression binding rate" value="1" constant="true"/>
<parameter metaid="iBioSim4" id="ka_f" name="Forward activation binding rate" value="0.0033" constant="true"/>
<parameter metaid="iBioSim5" id="ka_r" name="Reverse activation binding rate" value="1" constant="true"/>
<parameter metaid="iBioSim6" id="ko_f" name="Forward RNAP binding rate" value="0.033" constant="true"/>
<parameter metaid="iBioSim7" id="ko_r" name="Reverse RNAP binding rate" value="1" constant="true"/>
<parameter metaid="iBioSim8" id="kao_f" name="Forward activated RNAP binding rate" value="1" constant="true"/>
<parameter metaid="iBioSim9" id="kao_r" name="Reverse activated RNAP binding rate" value="1" constant="true"/>
<parameter metaid="iBioSim10" id="kc_f" name="Forward complex formation rate" value="0.05" constant="true"/>
<parameter metaid="iBioSim11" id="kc_r" name="Reverse complex formation rate" value="1" constant="true"/>
<parameter metaid="iBioSim12" id="kmdiff_f" name="Forward membrane diffusion rate" value="1" constant="true"/>
<parameter metaid="iBioSim13" id="kmdiff_r" name="Reverse membrane diffusion rate" value="0.01" constant="true"/>
<parameter metaid="iBioSim14" id="kd" name="Degradation rate" value="0.0075" constant="true"/>
<parameter metaid="iBioSim15" id="kecd" name="Extracellular degradation rate" value="0.005" constant="true"/>
<parameter metaid="iBioSim16" id="nc" name="Stoichiometry of binding" value="2" constant="true"/>
<parameter metaid="iBioSim17" id="nr" name="Initial RNAP count" value="30" constant="true"/>
<parameter metaid="iBioSim18" id="ko" name="Open complex production rate" value="0.05" constant="true"/>
<parameter metaid="iBioSim19" id="kb" name="Basal production rate" value="0.0001" constant="true"/>
<parameter metaid="iBioSim20" id="ng" name="Initial promoter count" value="2" constant="true"/>
<parameter metaid="iBioSim21" id="np" name="Stoichiometry of production" value="10" constant="true"/>
<parameter metaid="iBioSim22" id="ka" name="Activated production rate" value="0.25" constant="true"/>
<parameter metaid="iBioSim23" id="kecdiff" name="Extracellular diffusion rate" value="1" constant="true"/>
<parameter metaid="iBioSim24" id="Divide__locations" value="0" constant="false">
<annotation>
<array:array xmlns:array="http://www.fakeuri.com" array:C1="(0,0)"/>
</annotation>
</parameter>
</listOfParameters>
<layout:listOfLayouts xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:layout="http://www.sbml.org/sbml/level3/version1/layout/version1">
<layout:layout layout:id="iBioSim">
<layout:dimensions layout:width="0" layout:height="0"/>
<layout:listOfTextGlyphs>
<layout:textGlyph layout:id="TextGlyph__C1" layout:text="C1" layout:graphicalObject="Glyph__C1">
<layout:boundingBox>
<layout:position layout:x="30" layout:y="30"/>
<layout:dimensions layout:width="80" layout:height="40"/>
</layout:boundingBox>
</layout:textGlyph>
</layout:listOfTextGlyphs>
<layout:listOfAdditionalGraphicalObjects>
<layout:generalGlyph layout:id="Glyph__C1" layout:reference="C1">
<layout:boundingBox>
<layout:position layout:x="30" layout:y="30"/>
<layout:dimensions layout:width="80" layout:height="40"/>
</layout:boundingBox>
</layout:generalGlyph>
</layout:listOfAdditionalGraphicalObjects>
</layout:layout>
</layout:listOfLayouts>
<comp:listOfSubmodels>
<comp:submodel metaid="iBioSim25" comp:id="GRID__Divide" comp:modelRef="Divide">
<annotation>
<array:array xmlns:array="http://www.fakeuri.com" array:count="1"/>
</annotation>
</comp:submodel>
</comp:listOfSubmodels>
</model>
<comp:listOfExternalModelDefinitions>
<comp:externalModelDefinition comp:id="Divide" comp:source="file:Divide.xml" comp:md5="0a417cb64224a4ab9c9b82acab9082d4"/>
</comp:listOfExternalModelDefinitions>
</sbml>

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@ -0,0 +1,19 @@
#Graph Data
#Wed Jun 05 16:52:08 MDT 2013
visibleLegend=true
x.axis=time
auto.resize=true
y.max=1.0
plot.domain.grid.line.paint=-4144960
x.max=1.0
plot.background.paint=-1
y.axis=amount
chart.background.paint=-1118482
x.scale=0.1
LogY=false
LogX=false
title=TestDivide simulation results
plot.range.grid.line.paint=-4144960
y.min=-1.0
y.scale=0.1
x.min=-1.0

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#TestDivide Properties
#Tue Jun 04 17:34:33 MDT 2013
reb2sac.operator.max.concentration.threshold=15
reb2sac.qssa.condition.1=0.1
monte.carlo.simulation.time.step=100.0
monte.carlo.simulation.print.interval=1.0
monte.carlo.simulation.runs=1
reb2sac.simulation.method=monteCarlo
simulation.run.termination.decider=constraint
reb2sac.generate.statistics=false
monte.carlo.simulation.random.seed=314159
monte.carlo.simulation.time.limit=1000.0
simulation.printer.tracking.quantity=amount
reb2sac.iSSA.adaptive=true
simulation.printer=tsd.printer
monte.carlo.simulation.min.time.step=0.0
reb2sac.abstraction.method=none
reb2sac.abstraction.method.3.3=kinetic-law-constants-simplifier
reb2sac.abstraction.method.3.2=reversible-to-irreversible-transformer
reb2sac.abstraction.method.3.1=distribute-transformer
reb2sac.iSSA.number.paths=1
reb2sac.rapid.equilibrium.condition.2=0.1
reb2sac.diffusion.stoichiometry.amplification.value=1.0
reb2sac.rapid.equilibrium.condition.1=0.1
monte.carlo.simulation.out.dir=.
selected.simulator=SSA-Direct (Java)
reb2sac.iSSA.type=medianPath

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TestDivide.xml

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<?xml version="1.0" encoding="UTF-8"?>
<sbml xmlns="http://www.sbml.org/sbml/level3/version1/core" level="3" version="1">
<model metaid="iBioSim1" id="TestDivide" name="Created by iBioSim flatten routine" substanceUnits="mole" volumeUnits="litre">
<listOfUnitDefinitions>
<unitDefinition id="u_1_second_n1">
<listOfUnits>
<unit kind="second" exponent="-1" scale="0" multiplier="1"/>
</listOfUnits>
</unitDefinition>
</listOfUnitDefinitions>
<listOfCompartments>
<compartment id="Grid" spatialDimensions="3" size="1" constant="true">
<annotation>
<ibiosim:ibiosim xmlns:ibiosim="http://www.fakeuri.com" ibiosim:grid="(4,5)"/>
</annotation>
</compartment>
<compartment id="C1__Cell" spatialDimensions="3" size="1" constant="true"/>
</listOfCompartments>
<listOfSpecies>
<species metaid="C1__iBioSim2" id="C1__S0" compartment="C1__Cell" initialAmount="0" hasOnlySubstanceUnits="true" boundaryCondition="false" constant="false"/>
</listOfSpecies>
<listOfParameters>
<parameter metaid="iBioSim2" id="kr_f" name="Forward repression binding rate" value="0.5" constant="true"/>
<parameter metaid="iBioSim3" id="kr_r" name="Reverse repression binding rate" value="1" constant="true"/>
<parameter metaid="iBioSim4" id="ka_f" name="Forward activation binding rate" value="0.0033" constant="true"/>
<parameter metaid="iBioSim5" id="ka_r" name="Reverse activation binding rate" value="1" constant="true"/>
<parameter metaid="iBioSim6" id="ko_f" name="Forward RNAP binding rate" value="0.033" constant="true"/>
<parameter metaid="iBioSim7" id="ko_r" name="Reverse RNAP binding rate" value="1" constant="true"/>
<parameter metaid="iBioSim8" id="kao_f" name="Forward activated RNAP binding rate" value="1" constant="true"/>
<parameter metaid="iBioSim9" id="kao_r" name="Reverse activated RNAP binding rate" value="1" constant="true"/>
<parameter metaid="iBioSim10" id="kc_f" name="Forward complex formation rate" value="0.05" constant="true"/>
<parameter metaid="iBioSim11" id="kc_r" name="Reverse complex formation rate" value="1" constant="true"/>
<parameter metaid="iBioSim12" id="kmdiff_f" name="Forward membrane diffusion rate" value="1" constant="true"/>
<parameter metaid="iBioSim13" id="kmdiff_r" name="Reverse membrane diffusion rate" value="0.01" constant="true"/>
<parameter metaid="iBioSim14" id="kd" name="Degradation rate" value="0.0075" constant="true"/>
<parameter metaid="iBioSim15" id="kecd" name="Extracellular degradation rate" value="0.005" constant="true"/>
<parameter metaid="iBioSim16" id="nc" name="Stoichiometry of binding" value="2" constant="true"/>
<parameter metaid="iBioSim17" id="nr" name="Initial RNAP count" value="30" constant="true"/>
<parameter metaid="iBioSim18" id="ko" name="Open complex production rate" value="0.05" constant="true"/>
<parameter metaid="iBioSim19" id="kb" name="Basal production rate" value="0.0001" constant="true"/>
<parameter metaid="iBioSim20" id="ng" name="Initial promoter count" value="2" constant="true"/>
<parameter metaid="iBioSim21" id="np" name="Stoichiometry of production" value="10" constant="true"/>
<parameter metaid="iBioSim22" id="ka" name="Activated production rate" value="0.25" constant="true"/>
<parameter metaid="iBioSim23" id="kecdiff" name="Extracellular diffusion rate" value="1" constant="true"/>
<parameter metaid="iBioSim24" id="Divide__locations" value="0" constant="false">
<annotation>
<array:array xmlns:array="http://www.fakeuri.com" array:C1="(0,0)"/>
</annotation>
</parameter>
<parameter metaid="C1__iBioSim3" id="C1__kd" name="Degradation rate" value="0.0075" constant="true"/>
<parameter metaid="C1__iBioSim4" id="C1__np" name="Stoichiometry of production" value="10" constant="true"/>
<parameter metaid="C1__iBioSim5" id="C1__ko" name="Open complex production rate" value="0.05" constant="true"/>
</listOfParameters>
<listOfReactions>
<reaction id="Constitutive_production_C1__S0" reversible="false" fast="false" compartment="Grid">
<listOfProducts>
<speciesReference species="C1__S0" stoichiometry="10" constant="true"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<ci> kp </ci>
</math>
<listOfLocalParameters>
<localParameter id="kp" value="0.05"/>
</listOfLocalParameters>
</kineticLaw>
</reaction>
<reaction id="Degradation_C1__S0" reversible="false" fast="false" compartment="Grid">
<listOfReactants>
<speciesReference species="C1__S0" stoichiometry="1" constant="true"/>
</listOfReactants>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> kd </ci>
<ci> C1__S0 </ci>
</apply>
</math>
<listOfLocalParameters>
<localParameter id="kd" value="0.0075" units="u_1_second_n1"/>
</listOfLocalParameters>
</kineticLaw>
</reaction>
</listOfReactions>
<listOfEvents>
<event id="C1__SymmetricDivision__event0" useValuesFromTriggerTime="false">
<annotation>
<ibiosim:ibiosim xmlns:ibiosim="http://www.fakeuri.com" ibiosim:type="Symmetric Division"/>
</annotation>
<trigger initialValue="false" persistent="false">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<true/>
</math>
</trigger>
<delay>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<cn type="integer"> 200 </cn>
</math>
</delay>
</event>
<event id="C1__Death__event1" useValuesFromTriggerTime="false">
<annotation>
<ibiosim:ibiosim xmlns:ibiosim="http://www.fakeuri.com" ibiosim:type="Death"/>
</annotation>
<trigger initialValue="false" persistent="false">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<gt/>
<ci> C1__S0 </ci>
<cn type="integer"> 50 </cn>
</apply>
</math>
</trigger>
<delay>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<cn type="integer"> 100 </cn>
</math>
</delay>
</event>
</listOfEvents>
</model>
</sbml>

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@ -0,0 +1 @@
(("time"),(0.0),(100.0),(200.0),(300.0),(400.0),(500.0),(600.0),(700.0),(800.0),(900.0),(1000.0))

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#total time-limit
1 1

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Parameter Values:
kao_f = 1.000000
nr = 30.000000
C1__np = 10.000000
ka_f = 0.003300
nc = 2.000000
C1__kd = 0.007500
kr_f = 0.500000
kmdiff_r = 0.010000
kc_f = 0.050000
t = 0.000000
Degradation_C1__S0_kd = 0.007500
ng = 2.000000
Constitutive_production_C1__S0_kp = 0.050000
kmdiff_f = 1.000000
kecd = 0.005000
ko = 0.050000
ko_r = 1.000000
kao_r = 1.000000
ka = 0.250000
kecdiff = 1.000000
C1__ko = 0.050000
ka_r = 1.000000
kb = 0.000100
kr_r = 1.000000
np = 10.000000
time = 0.000000
ko_f = 0.033000
kc_r = 1.000000
kd = 0.007500
Divide__locations = 0.000000
Initial State Vector:
C1__S0 = 0.000000
Initial Reaction Rate Array:
0.050000
0.000000
Reaction Rate Equation Array:
Constitutive_production_C1__S0_kp
Degradation_C1__S0_kd * C1__S0
Reactant Matrix:
0.000000
1.000000
Delta Matrix:
10.000000
-1.000000

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@ -0,0 +1 @@
(("time"),(0.0),(100.0),(200.0),(300.0),(400.0),(500.0),(600.0),(700.0),(800.0),(900.0),(1000.0))

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<?xml version="1.0" encoding="UTF-8"?>
<sbml xmlns="http://www.sbml.org/sbml/level3/version1/core" xmlns:layout="http://www.sbml.org/sbml/level3/version1/layout/version1" xmlns:comp="http://www.sbml.org/sbml/level3/version1/comp/version1" level="3" version="1" layout:required="false" comp:required="true">
<model metaid="iBioSim1" id="TopLevel">
<listOfCompartments>
<compartment id="Cell" spatialDimensions="3" size="1" constant="true"/>
</listOfCompartments>
<layout:listOfLayouts xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:layout="http://www.sbml.org/sbml/level3/version1/layout/version1">
<layout:layout layout:id="iBioSim">
<layout:dimensions layout:width="0" layout:height="0"/>
<layout:listOfCompartmentGlyphs>
<layout:compartmentGlyph layout:id="Glyph__Cell" layout:compartment="Cell">
<layout:boundingBox>
<layout:position layout:x="0" layout:y="0"/>
<layout:dimensions layout:width="1070" layout:height="425"/>
</layout:boundingBox>
</layout:compartmentGlyph>
</layout:listOfCompartmentGlyphs>
<layout:listOfTextGlyphs>
<layout:textGlyph layout:id="TextGlyph__Cell" layout:text="Cell" layout:graphicalObject="Glyph__Cell">
<layout:boundingBox>
<layout:position layout:x="0" layout:y="0"/>
<layout:dimensions layout:width="1070" layout:height="425"/>
</layout:boundingBox>
</layout:textGlyph>
</layout:listOfTextGlyphs>
</layout:layout>
</layout:listOfLayouts>
<comp:listOfPorts>
<comp:port sboTerm="SBO:0000601" comp:idRef="Cell" comp:id="compartment__Cell"/>
</comp:listOfPorts>
</model>
</sbml>

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<?xml version='1.0' encoding='UTF-8' standalone='no'?>
<sbml xmlns="http://www.sbml.org/sbml/level3/version1/core" xmlns:layout="http://www.sbml.org/sbml/level3/version1/layout/version1" level="3" xmlns:comp="http://www.sbml.org/sbml/level3/version1/comp/version1" comp:required="true" version="1" layout:required="false">
<model id="case00987" name="case00987" metaid="iBioSim1">
<annotation>
</annotation>
<layout:listOfLayouts xmlns:layout="http://www.sbml.org/sbml/level3/version1/layout/version1" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<layout:layout layout:id="iBioSim">
<layout:dimensions layout:width="160" layout:height="230" layout:depth="0"/>
<layout:listOfAdditionalGraphicalObjects>
<layout:generalGlyph layout:reference="_E0" layout:id="Glyph___E0">
<layout:boundingBox>
<layout:position layout:x="80" layout:y="140"/>
<layout:dimensions layout:width="75" layout:height="25"/>
</layout:boundingBox>
<layout:listOfReferenceGlyphs>
<layout:referenceGlyph layout:id="Glyph___E0__product__k1" layout:role="product" layout:glyph="Glyph__k1"/>
</layout:listOfReferenceGlyphs>
</layout:generalGlyph>
<layout:generalGlyph layout:reference="k1" layout:id="Glyph__k1">
<layout:boundingBox>
<layout:position layout:x="100" layout:y="200"/>
<layout:dimensions layout:width="30" layout:height="30"/>
</layout:boundingBox>
</layout:generalGlyph>
</layout:listOfAdditionalGraphicalObjects>
<layout:listOfCompartmentGlyphs>
<layout:compartmentGlyph layout:id="Glyph__default_compartment" layout:compartment="default_compartment">
<layout:boundingBox>
<layout:position layout:x="0" layout:y="0"/>
<layout:dimensions layout:width="1070" layout:height="425"/>
</layout:boundingBox>
</layout:compartmentGlyph>
</layout:listOfCompartmentGlyphs>
<layout:listOfSpeciesGlyphs>
<layout:speciesGlyph layout:id="Glyph__A" layout:species="A">
<layout:boundingBox>
<layout:position layout:x="20" layout:y="40"/>
<layout:dimensions layout:width="100" layout:height="30"/>
</layout:boundingBox>
</layout:speciesGlyph>
<layout:speciesGlyph layout:id="Glyph__B" layout:species="B">
<layout:boundingBox>
<layout:position layout:x="40" layout:y="80"/>
<layout:dimensions layout:width="100" layout:height="30"/>
</layout:boundingBox>
</layout:speciesGlyph>
<layout:speciesGlyph layout:id="Glyph__C" layout:species="C">
<layout:boundingBox>
<layout:position layout:x="60" layout:y="120"/>
<layout:dimensions layout:width="100" layout:height="30"/>
</layout:boundingBox>
</layout:speciesGlyph>
</layout:listOfSpeciesGlyphs>
<layout:listOfTextGlyphs>
<layout:textGlyph layout:graphicalObject="Glyph__default_compartment" layout:id="TextGlyph__default_compartment" layout:text="default_compartment">
<layout:boundingBox>
<layout:position layout:x="0" layout:y="0"/>
<layout:dimensions layout:width="1070" layout:height="425"/>
</layout:boundingBox>
</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__A" layout:id="TextGlyph__A" layout:text="A">
<layout:boundingBox>
<layout:position layout:x="20" layout:y="40"/>
<layout:dimensions layout:width="100" layout:height="30"/>
</layout:boundingBox>
</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__B" layout:id="TextGlyph__B" layout:text="B">
<layout:boundingBox>
<layout:position layout:x="40" layout:y="80"/>
<layout:dimensions layout:width="100" layout:height="30"/>
</layout:boundingBox>
</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__C" layout:id="TextGlyph__C" layout:text="C">
<layout:boundingBox>
<layout:position layout:x="60" layout:y="120"/>
<layout:dimensions layout:width="100" layout:height="30"/>
</layout:boundingBox>
</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph___E0" layout:id="TextGlyph___E0" layout:text="_E0">
<layout:boundingBox>
<layout:position layout:x="80" layout:y="140"/>
<layout:dimensions layout:width="75" layout:height="25"/>
</layout:boundingBox>
</layout:textGlyph>
<layout:textGlyph layout:graphicalObject="Glyph__k1" layout:id="TextGlyph__k1" layout:text="k1">
<layout:boundingBox>
<layout:position layout:x="100" layout:y="200"/>
<layout:dimensions layout:width="30" layout:height="30"/>
</layout:boundingBox>
</layout:textGlyph>
</layout:listOfTextGlyphs>
</layout:layout>
</layout:listOfLayouts>
<listOfCompartments>
<compartment id="default_compartment" constant="true" spatialDimensions="3" sboTerm="SBO:0000410" size="1">
<annotation>
</annotation>
</compartment>
</listOfCompartments>
<listOfSpecies>
<species id="A" constant="false" initialAmount="1" hasOnlySubstanceUnits="true" metaid="iBioSim3" boundaryCondition="false" compartment="default_compartment"/>
<species id="B" constant="false" initialAmount="0" hasOnlySubstanceUnits="true" metaid="iBioSim4" boundaryCondition="false" compartment="default_compartment"/>
<species id="C" constant="false" initialAmount="0" hasOnlySubstanceUnits="true" metaid="iBioSim5" boundaryCondition="false" compartment="default_compartment"/>
</listOfSpecies>
<listOfParameters>
<parameter id="k1" constant="false" metaid="iBioSim2" value="0"/>
</listOfParameters>
<listOfReactions>
<reaction id="fast" metaid="iBioSim6" reversible="true" fast="true">
<listOfReactants>
<speciesReference constant="true" species="A" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="true" species="B" stoichiometry="1"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> k1 </ci>
<ci> A </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="slow" metaid="iBioSim7" reversible="true" fast="false">
<listOfReactants>
<speciesReference constant="true" species="B" stoichiometry="1"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="true" species="C" stoichiometry="1"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> k1 </ci>
<ci> B </ci>
</apply>
</math>
</kineticLaw>
</reaction>
</listOfReactions>
<listOfEvents>
<event id="_E0" useValuesFromTriggerTime="true">
<trigger persistent="true" initialValue="true">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<gt/>
<csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> t </csymbol>
<cn> 0.99 </cn>
</apply>
</math>
</trigger>
<listOfEventAssignments>
<eventAssignment variable="k1">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<cn type="integer"> 1 </cn>
</math>
</eventAssignment>
</listOfEventAssignments>
</event>
</listOfEvents>
</model>
</sbml>

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@ -0,0 +1,67 @@
<?xml version="1.0" encoding="UTF-8"?>
<sedML xmlns="http://sed-ml.org/" version="1" level="1">
<!--This file was generated by jlibsedml, version 1.2.0.-->
<listOfSimulations>
<uniformTimeCourse id="simulation_1" initialTime="0.0" outputStartTime="0.0" outputEndTime="2.0" numberOfPoints="11">
<algorithm kisaoID="KISAO:0000019" />
</uniformTimeCourse>
</listOfSimulations>
<listOfModels>
<model id="model_1" language="urn:sedml:language:sbml" source="case00987.xml" />
</listOfModels>
<listOfTasks>
<task id="task_1" modelReference="model_1" simulationReference="simulation_1" />
</listOfTasks>
<listOfDataGenerators>
<dataGenerator id="time_1" name="time">
<listOfVariables>
<variable id="time" taskReference="task_1" symbol="urn:sedml:symbol:time" />
</listOfVariables>
<math:math xmlns:math="http://www.w3.org/1998/Math/MathML">
<math:ci>time</math:ci>
</math:math>
</dataGenerator>
<dataGenerator id="A_1" name="A">
<listOfVariables>
<variable id="A" name="A" taskReference="task_1" target="/sbml:sbml/sbml:model/sbml:listOfSpecies/sbml:species[@id='A']" />
</listOfVariables>
<math:math xmlns:math="http://www.w3.org/1998/Math/MathML">
<math:ci>A</math:ci>
</math:math>
</dataGenerator>
<dataGenerator id="B_1" name="B">
<listOfVariables>
<variable id="B" name="B" taskReference="task_1" target="/sbml:sbml/sbml:model/sbml:listOfSpecies/sbml:species[@id='B']" />
</listOfVariables>
<math:math xmlns:math="http://www.w3.org/1998/Math/MathML">
<math:ci>B</math:ci>
</math:math>
</dataGenerator>
<dataGenerator id="C_1" name="C">
<listOfVariables>
<variable id="C" name="C" taskReference="task_1" target="/sbml:sbml/sbml:model/sbml:listOfSpecies/sbml:species[@id='C']" />
</listOfVariables>
<math:math xmlns:math="http://www.w3.org/1998/Math/MathML">
<math:ci>C</math:ci>
</math:math>
</dataGenerator>
</listOfDataGenerators>
<listOfOutputs>
<plot2D id="plot_1" name="Timecourse for test 00987">
<listOfCurves>
<curve id="c_A_1" name="A" logX="false" logY="false" xDataReference="time_1" yDataReference="A_1" />
<curve id="c_B_1" name="B" logX="false" logY="false" xDataReference="time_1" yDataReference="B_1" />
<curve id="c_C_1" name="C" logX="false" logY="false" xDataReference="time_1" yDataReference="C_1" />
</listOfCurves>
</plot2D>
<report id="report_1" name="Report for test 00987">
<listOfDataSets>
<dataSet dataReference="time_1" id="ds_time" label="Time" />
<dataSet dataReference="A_1" id="ds_A_1" label="A" />
<dataSet dataReference="B_1" id="ds_B_1" label="B" />
<dataSet dataReference="C_1" id="ds_C_1" label="C" />
</listOfDataSets>
</report>
</listOfOutputs>
</sedML>

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#Graph Data
#Fri Jun 07 14:29:46 MDT 2013
species.filled.2=true
species.filled.1=true
species.filled.0=true
chart.background.paint=-1118482
plot.background.paint=-1
species.connected.2=true
species.connected.1=true
species.connected.0=true
species.xnumber.2=0
y.max=1.0
species.xnumber.1=0
species.id.2=C (1)
species.xnumber.0=0
auto.resize=true
species.id.1=B (1)
species.id.0=A (1)
species.number.2=2
species.number.1=1
species.visible.2=true
y.axis=
species.number.0=0
species.visible.1=true
species.visible.0=true
species.paint.2=Black
species.paint.1=Black
species.directory.2=
species.paint.0=Black
species.directory.1=
species.directory.0=
x.max=1.0
title=Timecourse for test 00987
y.scale=0.1
x.scale=0.1
y.min=0.0
species.shape.2=Circle
species.name.2=C (1)
species.shape.1=Circle
species.name.1=B (1)
species.name.0=A (1)
species.shape.0=Circle
x.axis=
LogY=false
LogX=false
plot.range.grid.line.paint=-4144960
plot.domain.grid.line.paint=-4144960
species.run.number.2=run-1
species.run.number.1=run-1
species.run.number.0=run-1
visibleLegend=true
x.min=0.0

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#case00987 Properties
#Fri Jun 07 14:29:47 MDT 2013
monte.carlo.simulation.start.index=1
reb2sac.operator.max.concentration.threshold=15
reb2sac.qssa.condition.1=0.1
ode.simulation.number.steps=11
monte.carlo.simulation.runs=1
reb2sac.simulation.method=ODE
ode.simulation.time.limit=2.0
simulation.run.termination.decider=constraint
reb2sac.generate.statistics=false
monte.carlo.simulation.random.seed=314159
ode.simulation.time.step=inf
ode.simulation.out.dir=.
simulation.printer.tracking.quantity=amount
simulation.printer=tsd.printer
ode.simulation.absolute.error=1.0E-9
ode.simulation.min.time.step=0.0
reb2sac.abstraction.method=none
reb2sac.abstraction.method.3.1=kinetic-law-constants-simplifier
reb2sac.rapid.equilibrium.condition.2=0.1
reb2sac.diffusion.stoichiometry.amplification.value=1.0
reb2sac.rapid.equilibrium.condition.1=0.1
selected.simulator=rkf45

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case00987.xml

View file

@ -0,0 +1,169 @@
<?xml version="1.0" encoding="UTF-8"?>
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<listOfParameters>
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<listOfReactions>
<reaction metaid="iBioSim6" id="fast" reversible="true" fast="true">
<listOfReactants>
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<listOfProducts>
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<math xmlns="http://www.w3.org/1998/Math/MathML">
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<ci> A </ci>
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<reaction metaid="iBioSim7" id="slow" reversible="true" fast="false">
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View file

@ -0,0 +1,6 @@
Executing:
reb2sac --target.encoding=rkf45 /Users/myers/research/nobackup/workspace/BioSim/docs//Tutorial/case00987/case00987.xml
Total Simulation Time: 2.412381 seconds for case00987

View file

@ -0,0 +1 @@
(("time","A","B","C","k1"),(0, 1, 0, 0,0),(0.181818181818, 1, 0, 0,0),(0.363636363636, 1, 0, 0,0),(0.545454545455, 1, 0, 0,0),(0.727272727273, 1, 0, 0,0),(0.909090909091, 1, 0, 0,0),(1.09090909091, 3.33066907388e-16, 0.904024342939, 0.0959856570605,1),(1.27272727273, 3.33066907388e-16, 0.7537329339, 0.2462770661,1),(1.45454545455, 3.33066907388e-16, 0.628427033043, 0.371582966957,1),(1.63636363636, 3.33066907388e-16, 0.523952872556, 0.476057127444,1),(1.81818181818, 3.33066907388e-16, 0.436847236386, 0.563162763614,1),(2, 3.33066907388e-16, 0.36422265805, 0.63578734195,1))

View file

@ -0,0 +1,25 @@
Parameter Values:
t = 0.000000
k1 = 0.000000
time = 0.000000
Initial State Vector:
A = 1.000000
B = 0.000000
C = 0.000000
Initial Reaction Rate Array:
0.000000
0.000000
Reaction Rate Equation Array:
k1 * A
k1 * B
Reactant Matrix:
1.000000 0.000000 0.000000
0.000000 1.000000 0.000000
Delta Matrix:
-1.000000 1.000000 0.000000
0.000000 -1.000000 1.000000

View file

644
docs/OldTutorial/lambda.xml Normal file
View file

@ -0,0 +1,644 @@
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<cn type="integer"> 2 </cn>
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<parameter id="kc_f" constant="true" name="Forward complex formation rate" metaid="iBioSim11" value="0.05"/>
<parameter id="kc_r" constant="true" name="Reverse complex formation rate" metaid="iBioSim12" value="1"/>
<parameter id="nc" constant="true" name="Stoichiometry of binding" metaid="iBioSim13" value="2"/>
<parameter id="kr_f" constant="true" name="Forward repression binding rate" metaid="iBioSim14" value="0.5"/>
<parameter id="kr_r" constant="true" name="Reverse repression binding rate" metaid="iBioSim15" value="1"/>
<parameter id="ka_f" constant="true" name="Forward activation binding rate" metaid="iBioSim16" value="0.0033"/>
<parameter id="ka_r" constant="true" name="Reverse activation binding rate" metaid="iBioSim17" value="1"/>
<parameter id="ko_f" constant="true" name="Forward RNAP binding rate" metaid="iBioSim18" value="0.033"/>
<parameter id="ko_r" constant="true" name="Reverse RNAP binding rate" metaid="iBioSim19" value="1"/>
<parameter id="kao_f" constant="true" name="Forward activated RNAP binding rate" metaid="iBioSim20" value="1"/>
<parameter id="kao_r" constant="true" name="Reverse activated RNAP binding rate" metaid="iBioSim21" value="1"/>
<parameter id="nr" constant="true" name="Initial RNAP count" metaid="iBioSim22" value="30"/>
<parameter id="ko" constant="true" name="Open complex production rate" metaid="iBioSim23" value="0.05"/>
<parameter id="kb" constant="true" name="Basal production rate" metaid="iBioSim24" value="0.0001"/>
<parameter id="ng" constant="true" name="Initial promoter count" metaid="iBioSim25" value="2"/>
<parameter id="np" constant="true" name="Stoichiometry of production" metaid="iBioSim26" value="10"/>
<parameter id="ka" constant="true" name="Activated production rate" metaid="iBioSim27" value="0.25"/>
<parameter id="CI_total" constant="false" metaid="iBioSim9" value="0" units="nanoMole"/>
</listOfParameters>
<listOfRules>
<assignmentRule metaid="Total" variable="CI_total">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<ci> total </ci>
<ci> CI </ci>
<ci> CI2 </ci>
</apply>
</math>
</assignmentRule>
</listOfRules>
<listOfConstraints>
<constraint metaid="CI20">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<leq/>
<ci> CI </ci>
<cn type="integer"> 20 </cn>
</apply>
</math>
</constraint>
<constraint metaid="CII50">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<leq/>
<ci> CII </ci>
<cn type="integer"> 50 </cn>
</apply>
</math>
</constraint>
</listOfConstraints>
<listOfReactions>
<reaction id="Degradation_CI" metaid="iBioSim28" reversible="false" sboTerm="SBO:0000179" fast="false" compartment="Cell">
<listOfReactants>
<speciesReference constant="true" species="CI" stoichiometry="1"/>
</listOfReactants>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> kd </ci>
<ci> CI </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="Complex_CI2" metaid="iBioSim29" reversible="true" sboTerm="SBO:0000177" fast="false" compartment="Cell">
<listOfReactants>
<speciesReference constant="true" species="CI" stoichiometry="2"/>
</listOfReactants>
<listOfProducts>
<speciesReference constant="true" species="CI2" stoichiometry="1"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<minus/>
<apply>
<times/>
<ci> kc_f </ci>
<apply>
<power/>
<ci> CI </ci>
<ci> nc </ci>
</apply>
</apply>
<apply>
<times/>
<ci> kc_r </ci>
<ci> CI2 </ci>
</apply>
</apply>
</math>
<listOfLocalParameters>
<localParameter id="kc_f" value="0.1"/>
<localParameter id="kc_r" value="1"/>
</listOfLocalParameters>
</kineticLaw>
</reaction>
<reaction id="Degradation_CI2" metaid="iBioSim30" reversible="false" sboTerm="SBO:0000179" fast="false" compartment="Cell">
<listOfReactants>
<speciesReference constant="true" species="CI2" stoichiometry="1"/>
</listOfReactants>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> kd </ci>
<ci> CI2 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="Production_PR" metaid="iBioSim5" reversible="false" sboTerm="SBO:0000589" fast="false" compartment="Cell">
<annotation>
<ModelToSBOL xmlns="http://sbolstandard.org/modeltosbol/1.0#">
<rdf:RDF xmlns:mts="http://sbolstandard.org/modeltosbol/1.0#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="#iBioSim5">
<mts:DNAComponents>
<rdf:Seq>
<rdf:li rdf:resource="http://partsregistry.org/Part:BBa_R0051"/>
</rdf:Seq>
</mts:DNAComponents>
</rdf:Description>
</rdf:RDF>
</ModelToSBOL>
</annotation>
<listOfProducts>
<speciesReference constant="true" species="CII" stoichiometry="10"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="PR" sboTerm="SBO:0000598"/>
<modifierSpeciesReference species="CI2" sboTerm="SBO:0000020"/>
</listOfModifiers>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<times/>
<ci> PR </ci>
<ci> ko </ci>
<apply>
<divide/>
<ci> ko_f </ci>
<ci> ko_r </ci>
</apply>
<ci> nr </ci>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<times/>
<apply>
<divide/>
<ci> ko_f </ci>
<ci> ko_r </ci>
</apply>
<ci> nr </ci>
</apply>
<apply>
<power/>
<apply>
<times/>
<apply>
<divide/>
<ci> kr_CI2_f </ci>
<ci> kr_CI2_r </ci>
</apply>
<ci> CI2 </ci>
</apply>
<ci> nc_CI2_r </ci>
</apply>
</apply>
</apply>
</math>
<listOfLocalParameters>
<localParameter id="nc_CI2_r" value="1"/>
<localParameter id="kr_CI2_f" value="0.2165"/>
<localParameter id="kr_CI2_r" value="1"/>
<localParameter id="ko" value="0.014"/>
<localParameter id="ko_f" value="0.69422"/>
<localParameter id="ko_r" value="1"/>
</listOfLocalParameters>
</kineticLaw>
</reaction>
<reaction id="Degradation_CII" metaid="iBioSim31" reversible="false" sboTerm="SBO:0000179" fast="false" compartment="Cell">
<listOfReactants>
<speciesReference constant="true" species="CII" stoichiometry="1"/>
</listOfReactants>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> kd </ci>
<ci> CII </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="Production_PRE" metaid="iBioSim8" reversible="false" sboTerm="SBO:0000589" fast="false" compartment="Cell">
<listOfProducts>
<speciesReference constant="true" species="CI" stoichiometry="10"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="PRE" sboTerm="SBO:0000598"/>
<modifierSpeciesReference species="CII" sboTerm="SBO:0000459"/>
</listOfModifiers>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<times/>
<ci> PRE </ci>
<apply>
<plus/>
<apply>
<times/>
<ci> kb </ci>
<apply>
<divide/>
<ci> ko_f </ci>
<ci> ko_r </ci>
</apply>
<ci> nr </ci>
</apply>
<apply>
<times/>
<ci> ka </ci>
<apply>
<divide/>
<ci> kao_f </ci>
<ci> kao_r </ci>
</apply>
<ci> nr </ci>
<apply>
<power/>
<apply>
<times/>
<apply>
<divide/>
<ci> ka_CII_f </ci>
<ci> ka_CII_r </ci>
</apply>
<ci> CII </ci>
</apply>
<ci> nc_CII_a </ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<times/>
<apply>
<divide/>
<ci> ko_f </ci>
<ci> ko_r </ci>
</apply>
<ci> nr </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> kao_f </ci>
<ci> kao_r </ci>
</apply>
<ci> nr </ci>
<apply>
<power/>
<apply>
<times/>
<apply>
<divide/>
<ci> ka_CII_f </ci>
<ci> ka_CII_r </ci>
</apply>
<ci> CII </ci>
</apply>
<ci> nc_CII_a </ci>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfLocalParameters>
<localParameter id="kb" value="4E-5"/>
<localParameter id="ka" value="0.015"/>
<localParameter id="ko_f" value="0.01"/>
<localParameter id="ko_r" value="1"/>
<localParameter id="nc_CII_a" value="1"/>
<localParameter id="ka_CII_f" value="0.00161"/>
<localParameter id="ka_CII_r" value="1"/>
</listOfLocalParameters>
</kineticLaw>
</reaction>
</listOfReactions>
<listOfEvents>
<event id="CellDivision" useValuesFromTriggerTime="false">
<annotation>
<ibiosim:ibiosim ibiosim:type="Symmetric Division" xmlns:ibiosim="http://www.fakeuri.com"/>
</annotation>
<trigger persistent="false" initialValue="false">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<true/>
</math>
</trigger>
<delay>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<cn type="integer"> 2100 </cn>
</math>
</delay>
<listOfEventAssignments>
<eventAssignment variable="CI">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<ci> CI </ci>
<apply>
<ci> uniform </ci>
<cn type="integer"> 1 </cn>
<cn type="integer"> 2 </cn>
</apply>
</apply>
</math>
</eventAssignment>
<eventAssignment variable="CI2">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<ci> CI2 </ci>
<apply>
<ci> uniform </ci>
<cn type="integer"> 1 </cn>
<cn type="integer"> 2 </cn>
</apply>
</apply>
</math>
</eventAssignment>
<eventAssignment variable="CII">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<ci> CII </ci>
<apply>
<ci> uniform </ci>
<cn type="integer"> 1 </cn>
<cn type="integer"> 2 </cn>
</apply>
</apply>
</math>
</eventAssignment>
</listOfEventAssignments>
</event>
</listOfEvents>
</model>
</sbml>

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#lambda Properties
#Thu May 30 11:26:28 MDT 2013
file.stem=abs
monte.carlo.simulation.start.index=1
reb2sac.operator.max.concentration.threshold=15
reb2sac.qssa.condition.1=0.1
monte.carlo.simulation.time.step=inf
gcm.abstraction.method.2=operator-site-reduction-abstraction
monte.carlo.simulation.print.interval=10.0
gcm.abstraction.method.1=complex-formation-and-sequestering-abstraction
monte.carlo.simulation.runs=100
reb2sac.simulation.method=monteCarlo
simulation.run.termination.decider=constraint
reb2sac.generate.statistics=false
monte.carlo.simulation.random.seed=314159
monte.carlo.simulation.time.limit=2100.0
simulation.printer.tracking.quantity=amount
reb2sac.iSSA.adaptive=true
simulation.printer=tsd.printer
monte.carlo.simulation.min.time.step=0.0
reb2sac.abstraction.method=abs
reb2sac.abstraction.method.3.3=kinetic-law-constants-simplifier
reb2sac.abstraction.method.3.2=reversible-to-irreversible-transformer
reb2sac.abstraction.method.3.1=distribute-transformer
reb2sac.iSSA.number.paths=1
reb2sac.rapid.equilibrium.condition.2=0.1
reb2sac.diffusion.stoichiometry.amplification.value=1.0
reb2sac.rapid.equilibrium.condition.1=0.1
monte.carlo.simulation.out.dir=.
selected.simulator=gillespie
reb2sac.iSSA.type=medianPath

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<?xml version="1.0" encoding="UTF-8"?>
<sbml xmlns="http://www.sbml.org/sbml/level3/version1/core" level="3" version="1">
<model metaid="iBioSim1" id="lambda" name="Created by iBioSim flatten routine" substanceUnits="mole" timeUnits="second" volumeUnits="litre" extentUnits="nanoMole">
<listOfFunctionDefinitions>
<functionDefinition id="total" name="Find total molecules">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<lambda>
<bvar>
<ci> x </ci>
</bvar>
<bvar>
<ci> y </ci>
</bvar>
<apply>
<plus/>
<ci> x </ci>
<apply>
<times/>
<cn type="integer"> 2 </cn>
<ci> y </ci>
</apply>
</apply>
</lambda>
</math>
</functionDefinition>
<functionDefinition id="uniform" name="Uniform distribution">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<lambda>
<bvar>
<ci> a </ci>
</bvar>
<bvar>
<ci> b </ci>
</bvar>
<apply>
<divide/>
<apply>
<plus/>
<ci> a </ci>
<ci> b </ci>
</apply>
<cn type="integer"> 2 </cn>
</apply>
</lambda>
</math>
</functionDefinition>
</listOfFunctionDefinitions>
<listOfUnitDefinitions>
<unitDefinition id="nanoMole">
<listOfUnits>
<unit kind="mole" exponent="1" scale="-9" multiplier="1"/>
</listOfUnits>
</unitDefinition>
<unitDefinition id="microLitre">
<listOfUnits>
<unit kind="litre" exponent="1" scale="-3" multiplier="1"/>
</listOfUnits>
</unitDefinition>
<unitDefinition id="u_1_second_n1">
<listOfUnits>
<unit kind="second" exponent="-1" scale="0" multiplier="1"/>
</listOfUnits>
</unitDefinition>
<unitDefinition id="u_1_mole_n1">
<listOfUnits>
<unit kind="mole" exponent="-1" scale="0" multiplier="1"/>
</listOfUnits>
</unitDefinition>
<unitDefinition id="u_1_mole_n1_1_second_n1">
<listOfUnits>
<unit kind="mole" exponent="-1" scale="0" multiplier="1"/>
<unit kind="second" exponent="-1" scale="0" multiplier="1"/>
</listOfUnits>
</unitDefinition>
</listOfUnitDefinitions>
<listOfCompartments>
<compartment id="Cell" spatialDimensions="3" size="1" constant="true"/>
</listOfCompartments>
<listOfSpecies>
<species metaid="iBioSim2" id="CI" compartment="Cell" initialAmount="0" hasOnlySubstanceUnits="true" boundaryCondition="false" constant="false"/>
<species metaid="iBioSim4" sboTerm="SBO:0000590" id="PR" compartment="Cell" initialAmount="2" hasOnlySubstanceUnits="true" boundaryCondition="false" constant="false"/>
<species metaid="iBioSim6" id="CII" compartment="Cell" initialAmount="0" hasOnlySubstanceUnits="true" boundaryCondition="false" constant="false"/>
<species metaid="iBioSim7" sboTerm="SBO:0000590" id="PRE" compartment="Cell" initialAmount="2" hasOnlySubstanceUnits="true" boundaryCondition="false" constant="false"/>
</listOfSpecies>
<listOfParameters>
<parameter metaid="iBioSim10" id="kd" name="Degradation rate" value="0.0075" constant="true"/>
<parameter metaid="iBioSim11" id="kc_f" name="Forward complex formation rate" value="0.05" constant="true"/>
<parameter metaid="iBioSim12" id="kc_r" name="Reverse complex formation rate" value="1" constant="true"/>
<parameter metaid="iBioSim13" id="nc" name="Stoichiometry of binding" value="2" constant="true"/>
<parameter metaid="iBioSim14" id="kr_f" name="Forward repression binding rate" value="0.5" constant="true"/>
<parameter metaid="iBioSim15" id="kr_r" name="Reverse repression binding rate" value="1" constant="true"/>
<parameter metaid="iBioSim16" id="ka_f" name="Forward activation binding rate" value="0.0033" constant="true"/>
<parameter metaid="iBioSim17" id="ka_r" name="Reverse activation binding rate" value="1" constant="true"/>
<parameter metaid="iBioSim18" id="ko_f" name="Forward RNAP binding rate" value="0.033" constant="true"/>
<parameter metaid="iBioSim19" id="ko_r" name="Reverse RNAP binding rate" value="1" constant="true"/>
<parameter metaid="iBioSim20" id="kao_f" name="Forward activated RNAP binding rate" value="1" constant="true"/>
<parameter metaid="iBioSim21" id="kao_r" name="Reverse activated RNAP binding rate" value="1" constant="true"/>
<parameter metaid="iBioSim22" id="nr" name="Initial RNAP count" value="30" constant="true"/>
<parameter metaid="iBioSim23" id="ko" name="Open complex production rate" value="0.05" constant="true"/>
<parameter metaid="iBioSim24" id="kb" name="Basal production rate" value="0.0001" constant="true"/>
<parameter metaid="iBioSim25" id="ng" name="Initial promoter count" value="2" constant="true"/>
<parameter metaid="iBioSim26" id="np" name="Stoichiometry of production" value="10" constant="true"/>
<parameter metaid="iBioSim27" id="ka" name="Activated production rate" value="0.25" constant="true"/>
<parameter metaid="iBioSim9" id="CI_total" value="0" units="nanoMole" constant="false"/>
</listOfParameters>
<listOfReactions>
<reaction id="Degradation_CI" reversible="false" fast="false" compartment="Cell">
<listOfReactants>
<speciesReference species="CI" stoichiometry="1" constant="true"/>
</listOfReactants>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> kd </ci>
<ci> CI </ci>
</apply>
</math>
<listOfLocalParameters>
<localParameter id="kd" value="0.0075" units="u_1_second_n1"/>
</listOfLocalParameters>
</kineticLaw>
</reaction>
<reaction id="Degradation_CII" reversible="false" fast="false" compartment="Cell">
<listOfReactants>
<speciesReference species="CII" stoichiometry="1" constant="true"/>
</listOfReactants>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> kd </ci>
<ci> CII </ci>
</apply>
</math>
<listOfLocalParameters>
<localParameter id="kd" value="0.0075" units="u_1_second_n1"/>
</listOfLocalParameters>
</kineticLaw>
</reaction>
<reaction id="R_abstracted_production_PRE" reversible="false" fast="false" compartment="Cell">
<listOfProducts>
<speciesReference species="CI" stoichiometry="10" constant="true"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="CII"/>
</listOfModifiers>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<times/>
<ci> ng__PRE </ci>
<apply>
<plus/>
<apply>
<times/>
<ci> kb__PRE </ci>
<ci> Ko__PRE </ci>
<ci> RNAP </ci>
</apply>
<apply>
<times/>
<ci> ka__CII_PRE </ci>
<ci> RNAP </ci>
<apply>
<power/>
<apply>
<times/>
<ci> Ka__CII_PRE </ci>
<ci> CII </ci>
</apply>
<ci> nc__CII_PRE </ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<times/>
<ci> Ko__PRE </ci>
<ci> RNAP </ci>
</apply>
<apply>
<times/>
<ci> Kao__PRE </ci>
<ci> RNAP </ci>
<apply>
<power/>
<apply>
<times/>
<ci> Ka__CII_PRE </ci>
<ci> CII </ci>
</apply>
<ci> nc__CII_PRE </ci>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfLocalParameters>
<localParameter id="RNAP" value="30" units="u_1_mole_n1"/>
<localParameter id="ng__PRE" value="2" units="u_1_mole_n1"/>
<localParameter id="kb__PRE" value="4e-05" units="u_1_second_n1"/>
<localParameter id="Ko__PRE" value="0.01" units="u_1_mole_n1"/>
<localParameter id="Kao__PRE" value="1" units="u_1_mole_n1"/>
<localParameter id="nc__CII_PRE" value="1" units="dimensionless"/>
<localParameter id="Ka__CII_PRE" value="0.00161" units="u_1_mole_n1"/>
<localParameter id="ka__CII_PRE" value="0.015" units="u_1_second_n1"/>
</listOfLocalParameters>
</kineticLaw>
</reaction>
<reaction id="R_abstracted_production_PR" reversible="false" fast="false" compartment="Cell">
<listOfProducts>
<speciesReference species="CII" stoichiometry="10" constant="true"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="CI"/>
</listOfModifiers>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<apply>
<times/>
<ci> ko__PR </ci>
<ci> ng__PR </ci>
<ci> Ko__PR </ci>
<ci> RNAP </ci>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<times/>
<ci> Ko__PR </ci>
<ci> RNAP </ci>
</apply>
<apply>
<power/>
<apply>
<times/>
<ci> Kr__CI2_PR </ci>
<apply>
<power/>
<apply>
<divide/>
<ci> kf_c__CI2 </ci>
<apply>
<plus/>
<ci> kr_c__CI2 </ci>
<ci> kd__CI2 </ci>
</apply>
</apply>
<apply>
<minus/>
<ci> nc__CI_CI2 </ci>
<cn type="integer"> 1 </cn>
</apply>
</apply>
<apply>
<power/>
<ci> CI </ci>
<ci> nc__CI_CI2 </ci>
</apply>
</apply>
<ci> nc__CI2_PR </ci>
</apply>
</apply>
</apply>
</math>
<listOfLocalParameters>
<localParameter id="RNAP" value="30" units="u_1_mole_n1"/>
<localParameter id="ng__PR" value="2" units="u_1_mole_n1"/>
<localParameter id="Ko__PR" value="0.69422" units="u_1_mole_n1"/>
<localParameter id="ko__PR" value="0.014" units="u_1_second_n1"/>
<localParameter id="kf_c__CI2" value="0.1" units="u_1_mole_n1_1_second_n1"/>
<localParameter id="kd__CI2" value="0.0075" units="u_1_second_n1"/>
<localParameter id="kr_c__CI2" value="1" units="u_1_second_n1"/>
<localParameter id="nc__CI_CI2" value="2" units="dimensionless"/>
<localParameter id="nc__CI2_PR" value="1" units="dimensionless"/>
<localParameter id="Kr__CI2_PR" value="0.2165" units="u_1_mole_n1"/>
</listOfLocalParameters>
</kineticLaw>
</reaction>
</listOfReactions>
</model>
</sbml>

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Executing:
reb2sac --target.encoding=gillespie /Users/myers/research/nobackup/workspace/BioSim/docs/Tutorial/lambda/abs/lambda.xml
Total Simulation Time: 1.605304 second for lambda abs

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